Literature DB >> 23640426

Pituitary adenoma with mucin cells in a man with an unusual presentation of Carney complex.

Gabrielle A Yeaney1, Jillene M Brathwaite, Matthew L Dashnaw, G Edward Vates, Laura M Calvi.   

Abstract

We describe a 44-year-old man with infertility, acromegaly, and hypergonadotropic hypogonadism. Clinical examination of the patient revealed hyperpigmented macules on the lips, buccal mucosa, and face which were histologically confirmed as cutaneous myxomas and blue nevi. Ultrasound revealed testicular calcifications and multiple hypoechoic thyroid nodules. MR imaging showed a pituitary microadenoma and resection revealed it to be a growth hormone and prolactin-secreting adenoma with the unusual finding of admixed individual mucin-producing cells. We discuss mucin cells in pituitary adenoma, an unreported pathologic finding in a patient with Carney complex.

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Year:  2013        PMID： 23640426     DOI： 10.1007/s12022-013-9247-x

Source DB:  PubMed          Journal:  Endocr Pathol        ISSN： 1046-3976            Impact factor:   3.943


  14 in total

1.  Intraductal papillary mucinous tumor of the pancreas in 2 twin brothers diagnosed as having the carney complex.

Authors:  Claire Pery; Salvatore Avallone; Nicolas Regenet; Emmanuel Coron; Joël Le Borgne
Journal:  Pancreas       Date:  2009-03       Impact factor: 3.327

2.  Pituitary pathology in Carney complex patients.

Authors:  Sotirios G Stergiopoulos; Mones S Abu-Asab; Maria Tsokos; Constantine A Stratakis
Journal:  Pituitary       Date:  2004       Impact factor: 4.107

Review 3.  Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation.

Authors:  C A Stratakis; L S Kirschner; J A Carney
Journal:  J Clin Endocrinol Metab       Date:  2001-09       Impact factor: 5.958

4.  Pancreatic ductal and acinar cell neoplasms in Carney complex: a possible new association.

Authors:  Sébastien Gaujoux; Frédérique Tissier; Bruno Ragazzon; Vinciane Rebours; Emmanouil Saloustros; Karine Perlemoine; Caroline Vincent-Dejean; Guillaume Meurette; Elisabeth Cassagnau; Bertrand Dousset; Xavier Bertagna; Anelia Horvath; Benoit Terris; J Aidan Carney; Constantine A Stratakis; Jérôme Bertherat
Journal:  J Clin Endocrinol Metab       Date:  2011-09-07       Impact factor: 5.958

5.  Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex).

Authors:  S D Pack; L S Kirschner; E Pak; Z Zhuang; J A Carney; C A Stratakis
Journal:  J Clin Endocrinol Metab       Date:  2000-10       Impact factor: 5.958

6.  Cystic prolactinoma: a variant of "transitional cell tumor" of the pituitary.

Authors:  G S Pearl; Y Takei; M Kurisaka; S Seyama; G T Tindall
Journal:  Am J Surg Pathol       Date:  1981-01       Impact factor: 6.394

7.  Transitional cell tumor of the pituitary gland developing from a Rathke's cleft cyst.

Authors:  J J Kepes
Journal:  Cancer       Date:  1978-01       Impact factor: 6.860

8.  Identification of a novel genetic locus for familial cardiac myxomas and Carney complex.

Authors:  M Casey; C Mah; A D Merliss; L S Kirschner; S E Taymans; A E Denio; B Korf; A D Irvine; A Hughes; J A Carney; C A Stratakis; C T Basson
Journal:  Circulation       Date:  1998-12-08       Impact factor: 29.690

9.  Pituitary adenoma with rich folliculo-stellate cells and mucin-producing epithelia arising in a 2-year-old girl.

Authors:  Hye Sook Min; Seung June Lee; Seung-Ki Kim; Sung-Hye Park
Journal:  Pathol Int       Date:  2007-09       Impact factor: 2.534

10.  Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2.

Authors:  C A Stratakis; J A Carney; J P Lin; D A Papanicolaou; M Karl; D L Kastner; E Pras; G P Chrousos
Journal:  J Clin Invest       Date:  1996-02-01       Impact factor: 14.808
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  2 in total

Review 1.  Acromegaly in Carney complex.

Authors:  T Cuny; T T Mac; P Romanet; H Dufour; I Morange; F Albarel; A Lagarde; F Castinetti; T Graillon; M O North; A Barlier; T Brue
Journal:  Pituitary       Date:  2019-10       Impact factor: 4.107

2.  Geographic-Related Differences of Pituitary Adenomas Hormone Profile: Analysis of Two Groups Coming from Southeastern and Eastern Europe.

Authors:  Anca Maria Cimpean; Eugen Melnic; Bogdan Bălinişteanu; Ana Corlan; Mihail Coculescu; Sergiu Rusu; Marius Raica
Journal:  Int J Endocrinol       Date:  2015-05-11       Impact factor: 3.257
  2 in total

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