Literature DB >> 23637225

Evidence-based recommendations for the diagnosis and treatment of pediatric acne.

Lawrence F Eichenfield1, Andrew C Krakowski, Caroline Piggott, James Del Rosso, Hilary Baldwin, Sheila Fallon Friedlander, Moise Levy, Anne Lucky, Anthony J Mancini, Seth J Orlow, Albert C Yan, Keith K Vaux, Guy Webster, Andrea L Zaenglein, Diane M Thiboutot.   

Abstract

INTRODUCTION: Acne vulgaris is one of the most common skin conditions in children and adolescents. The presentation, differential diagnosis, and association of acne with systemic pathology differs by age of presentation. Current acknowledged guidelines for the diagnosis and management of pediatric acne are lacking, and there are variations in management across the spectrum of primary and specialty care. The American Acne and Rosacea Society convened a panel of pediatric dermatologists, pediatricians, and dermatologists with expertise in acne to develop recommendations for the management of pediatric acne and evidence-based treatment algorithms.
METHODS: Ten major topic areas in the diagnosis and treatment of pediatric acne were identified. A thorough literature search was performed and articles identified, reviewed, and assessed for evidence grading. Each topic area was assigned to 2 expert reviewers who developed and presented summaries and recommendations for critique and editing. Furthermore, the Strength of Recommendation Taxonomy, including ratings for the strength of recommendation for a body of evidence, was used throughout for the consensus recommendations for the evaluation and management of pediatric acne. Practical evidence-based treatment algorithms also were developed.
RESULTS: Recommendations were put forth regarding the classification, diagnosis, evaluation, and management of pediatric acne, based on age and pubertal status. Treatment considerations include the use of over-the-counter products, topical benzoyl peroxide, topical retinoids, topical antibiotics, oral antibiotics, hormonal therapy, and isotretinoin. Simplified treatment algorithms and recommendations are presented in detail for adolescent, preadolescent, infantile, and neonatal acne. Other considerations, including psychosocial effects of acne, adherence to treatment regimens, and the role of diet and acne, also are discussed.
CONCLUSIONS: These expert recommendations by the American Acne and Rosacea Society as reviewed and endorsed by the American Academy of Pediatrics constitute the first detailed, evidence-based clinical guidelines for the management of pediatric acne including issues of special concern when treating pediatric patients.

Entities:  

Keywords:  AARS; American Acne and Rosacea Society; acne algorithm; acne guidelines; acne treatment; bacterial resistance; benzoyl peroxide; combination acne therapy; hormonal therapy; infantile acne; isotretinoin; mid-childhood acne; neonatal acne; pediatric acne; preadolescent acne; retinoids

Mesh:

Substances:

Year:  2013        PMID: 23637225     DOI: 10.1542/peds.2013-0490B

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  21 in total

Review 1.  Polycystic ovary syndrome in adolescence: diagnostic and therapeutic strategies.

Authors:  Manmohan K Kamboj; Andrea E Bonny
Journal:  Transl Pediatr       Date:  2017-10

Review 2.  The role of skin care as an integral component in the management of acne vulgaris: part 1: the importance of cleanser and moisturizer ingredients, design, and product selection.

Authors:  James Q Del Rosso
Journal:  J Clin Aesthet Dermatol       Date:  2013-12

3.  Infantile acne.

Authors:  Michael Samycia; Joseph M Lam
Journal:  CMAJ       Date:  2016-11-21       Impact factor: 8.262

4.  The use of isotretinoin in the treatment of acne vulgaris: clinical considerations and future directions.

Authors:  James J Leyden; James Q Del Rosso; Eric W Baum
Journal:  J Clin Aesthet Dermatol       Date:  2014-02

5.  Once-daily Dapsone 7.5% Gel for the Treatment of Acne Vulgaris in Preadolescent Patients: A Phase IV, Open-label, 12-week Study.

Authors:  Angela Yen Moore; Edward L Lain; Amy McMichael; Leon Kircik; Andrea L Zaenglein; Adelaide A Hebert; Ayman Grada
Journal:  J Clin Aesthet Dermatol       Date:  2021-04-01

6.  Antimicrobials and Antiepileptics Are the Leading Causes of Idiosyncratic Drug-induced Liver Injury in American Children.

Authors:  Frank DiPaola; Jean P Molleston; Jiezhun Gu; Elizabeth T Cirulli; Naga Chalasani; Huiman Barnhart; David E Kleiner; Jay H Hoofnagle; Robert J Fontana
Journal:  J Pediatr Gastroenterol Nutr       Date:  2019-08       Impact factor: 2.839

Review 7.  Acne, the Skin Microbiome, and Antibiotic Treatment.

Authors:  Haoxiang Xu; Huiying Li
Journal:  Am J Clin Dermatol       Date:  2019-06       Impact factor: 7.403

Review 8.  Oral Doxycycline in the Management of Acne Vulgaris: Current Perspectives on Clinical Use and Recent Findings with a New Double-scored Small Tablet Formulation.

Authors:  James Q Del Rosso
Journal:  J Clin Aesthet Dermatol       Date:  2015-05

Review 9.  Current concepts in psychodermatology.

Authors:  Madhulika A Gupta; Aditya K Gupta
Journal:  Curr Psychiatry Rep       Date:  2014-06       Impact factor: 5.285

Review 10.  Acne and the Lesbian, Gay, Bisexual, or Transgender Teenager.

Authors:  Laura Ragmanauskaite; Benjamin Kahn; BaoChau Ly; Howa Yeung
Journal:  Dermatol Clin       Date:  2019-11-26       Impact factor: 3.478

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