Literature DB >> 23636984

Recent advances in neuroimaging biomarkers in geriatric psychiatry.

Abhisek C Khandai1, Howard J Aizenstein.   

Abstract

Neuroimaging, both structural and functional, serve as useful adjuncts to clinical assessment, and can provide objective, reliable means of assessing disease presence and process in the aging population. In the following review we briefly explain current imaging methodologies. Then, we analyze recent developments in developing neuroimaging biomarkers for two highly prevalent disorders in the elderly population- Alzheimer's disease (AD) and late-life depression (LLD). In AD, efforts are focused on early diagnosis through in vivo visualization of disease pathophysiology. In LLD, recent imaging evidence supports the role of white matter ischemic changes in the pathogenesis of depression in the elderly, the "vascular hypothesis." Finally, we discuss potential roles for neuroimaging biomarkers in geriatric psychiatry in the future.

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Year:  2013        PMID： 23636984      PMCID： PMC3667151          DOI： 10.1007/s11920-013-0360-9

Source DB:  PubMed          Journal:  Curr Psychiatry Rep        ISSN： 1523-3812            Impact factor:   5.285


  71 in total

1.  The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.

Authors:  Guy M McKhann; David S Knopman; Howard Chertkow; Bradley T Hyman; Clifford R Jack; Claudia H Kawas; William E Klunk; Walter J Koroshetz; Jennifer J Manly; Richard Mayeux; Richard C Mohs; John C Morris; Martin N Rossor; Philip Scheltens; Maria C Carrillo; Bill Thies; Sandra Weintraub; Creighton H Phelps
Journal:  Alzheimers Dement       Date:  2011-04-21       Impact factor: 21.566

2.  Transforming cerebrospinal fluid Aβ42 measures into calculated Pittsburgh Compound B units of brain Aβ amyloid.

Authors:  Stephen D Weigand; Prashanthi Vemuri; Heather J Wiste; Matthew L Senjem; Vernon S Pankratz; Paul S Aisen; Michael W Weiner; Ronald C Petersen; Leslie M Shaw; John Q Trojanowski; David S Knopman; Clifford R Jack
Journal:  Alzheimers Dement       Date:  2011-02-01       Impact factor: 21.566

3.  Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study.

Authors:  Henryk Barthel; Hermann-Josef Gertz; Stefan Dresel; Oliver Peters; Peter Bartenstein; Katharina Buerger; Florian Hiemeyer; Sabine M Wittemer-Rump; John Seibyl; Cornelia Reininger; Osama Sabri
Journal:  Lancet Neurol       Date:  2011-04-08       Impact factor: 44.182

4.  Depressive symptoms, brain volumes and subclinical cerebrovascular disease in postmenopausal women: the Women's Health Initiative MRI Study.

Authors:  Joseph S Goveas; Mark A Espeland; Patricia Hogan; Vonetta Dotson; Sergey Tarima; Laura H Coker; Judith Ockene; Robert Brunner; Nancy F Woods; Sylvia Wassertheil-Smoller; Jane M Kotchen; Susan Resnick
Journal:  J Affect Disord       Date:  2011-02-24       Impact factor: 4.839

5.  Neuroanatomical and neuropsychological features of elderly euthymic depressed patients with early- and late-onset.

Authors:  Christophe Delaloye; Guenaël Moy; Fabienne de Bilbao; Sandra Baudois; Kerstin Weber; Françoise Hofer; Claire Ragno Paquier; Alessia Donati; Alessandra Canuto; Umberto Giardini; Armin von Gunten; Raluca Iona Stancu; François Lazeyras; Philippe Millet; Philip Scheltens; Panteleimon Giannakopoulos; Gabriel Gold
Journal:  J Neurol Sci       Date:  2010-09-17       Impact factor: 3.181

6.  Reduction of dorsolateral prefrontal cortex gray matter in late-life depression.

Authors:  Cheng-Chen Chang; Shun-Chieh Yu; Douglas R McQuoid; Denise F Messer; Warren D Taylor; Kulpreet Singh; Brian D Boyd; K Ranga R Krishnan; James R MacFall; David C Steffens; Martha E Payne
Journal:  Psychiatry Res       Date:  2011-05-18       Impact factor: 3.222

7.  Change in hippocampal volume on magnetic resonance imaging and cognitive decline among older depressed and nondepressed subjects in the neurocognitive outcomes of depression in the elderly study.

Authors:  David C Steffens; Douglas R McQuoid; Martha E Payne; Guy G Potter
Journal:  Am J Geriatr Psychiatry       Date:  2011-01       Impact factor: 4.105

8.  Depression, hypothalamic pituitary adrenal axis, and hippocampal and entorhinal cortex volumes--the SMART Medea study.

Authors:  Lotte Gerritsen; Hannie C Comijs; Yolanda van der Graaf; Arnoud J G Knoops; Brenda W J H Penninx; Mirjam I Geerlings
Journal:  Biol Psychiatry       Date:  2011-03-24       Impact factor: 13.382

9.  Use of florbetapir-PET for imaging beta-amyloid pathology.

Authors:  Christopher M Clark; Julie A Schneider; Barry J Bedell; Thomas G Beach; Warren B Bilker; Mark A Mintun; Michael J Pontecorvo; Franz Hefti; Alan P Carpenter; Matthew L Flitter; Michael J Krautkramer; Hank F Kung; R Edward Coleman; P Murali Doraiswamy; Adam S Fleisher; Marwan N Sabbagh; Carl H Sadowsky; Eric P Reiman; P Eric M Reiman; Simone P Zehntner; Daniel M Skovronsky
Journal:  JAMA       Date:  2011-01-19       Impact factor: 56.272

10.  Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden.

Authors:  Alexander Drzezga; J Alex Becker; Koene R A Van Dijk; Aishwarya Sreenivasan; Tanveer Talukdar; Caroline Sullivan; Aaron P Schultz; Jorge Sepulcre; Deepti Putcha; Doug Greve; Keith A Johnson; Reisa A Sperling
Journal:  Brain       Date:  2011-04-13       Impact factor: 13.501
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  3 in total

Review 1.  Artificial intelligence approaches to predicting and detecting cognitive decline in older adults: A conceptual review.

Authors:  Sarah A Graham; Ellen E Lee; Dilip V Jeste; Ryan Van Patten; Elizabeth W Twamley; Camille Nebeker; Yasunori Yamada; Ho-Cheol Kim; Colin A Depp
Journal:  Psychiatry Res       Date:  2019-12-09       Impact factor: 3.222

Review 2.  Principles and management of neuropsychiatric symptoms in Alzheimer's dementia.

Authors:  Milap A Nowrangi; Constantine G Lyketsos; Paul B Rosenberg
Journal:  Alzheimers Res Ther       Date:  2015-01-29       Impact factor: 6.982

3.  Brain Morphometry Estimation: From Hours to Seconds Using Deep Learning.

Authors:  Michael Rebsamen; Yannick Suter; Roland Wiest; Mauricio Reyes; Christian Rummel
Journal:  Front Neurol       Date:  2020-04-08       Impact factor: 4.003
  3 in total

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