Literature DB >> 23635260

Feasibility of a simple method of hybrid collimation for megavoltage grid therapy.

Pedro Almendral1, Pedro J Mancha, Daniel Roberto.   

Abstract

PURPOSE: Megavoltage grid therapy is currently delivered with step-and-shoot multisegment techniques or using a high attenuation block with divergent holes. However, the commercial availability of grid blocks is limited, their construction is difficult, and step-and-shoot techniques require longer treatment times and are not practical with some multileaf collimators. This work studies the feasibility of a hybrid collimation system for grid therapy that does not require multiple segments and can be easily implemented with widely available technical means.
METHODS: The authors have developed a system to generate a grid of beamlets by the simultaneous use of two perpendicular sets of equally spaced leaves that project stripe patterns in orthogonal directions. One of them is generated with the multileaf collimator integrated in the accelerator and the other with an in-house made collimator constructed with a low melting point alloy commonly available at radiation oncology departments. The characteristics of the grid fields for 6 and 18 MV have been studied with a shielded diode, an unshielded diode, and radiochromic film.
RESULTS: The grid obtained with the hybrid collimation is similar to some of the grids used clinically with respect to the beamlet size (about 1 cm) and the percentage of open beam (1/4 of the total field). The grid fields are less penetrating than the open fields of the same energy. Depending on the depth and the direction of the profiles (diagonal or along the principal axes), the measured valley-to-peak dose ratios range from 5% to 16% for 6 MV and from 9% to 20% for 18 MV. All the detectors yield similar results in the measurement of profiles and percent depth dose, but the shielded diode seems to overestimate the output factors.
CONCLUSIONS: The combination of two stripe pattern collimators in orthogonal directions is a feasible method to obtain two-dimensional arrays of beamlets and has potential usefulness as an efficient way to deliver grid therapy. The implementation of this method is technically simpler than the construction of a conventional grid block.

Mesh:

Year:  2013        PMID: 23635260     DOI: 10.1118/1.4801902

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  5 in total

Review 1.  A Current Review of Spatial Fractionation: Back to the Future?

Authors:  Cole Billena; Atif J Khan
Journal:  Int J Radiat Oncol Biol Phys       Date:  2019-01-23       Impact factor: 7.038

2.  Grid Block Design Based on Monte Carlo Simulated Dosimetry, the Linear Quadratic and Hug-Kellerer Radiobiological Models.

Authors:  Somayeh Gholami; Hassan Ali Nedaie; Francesco Longo; Mohammad Reza Ay; Sharifeh A Dini; Ali S Meigooni
Journal:  J Med Phys       Date:  2017 Oct-Dec

3.  A novel, yet simple MLC-based 3D-crossfire technique for spatially fractionated GRID therapy treatment of deep-seated bulky tumors.

Authors:  Damodar Pokhrel; Matthew Halfman; Lana Sanford; Quan Chen; Mahesh Kudrimoti
Journal:  J Appl Clin Med Phys       Date:  2020-02-08       Impact factor: 2.102

4.  Conebeam CT-guided 3D MLC-based spatially fractionated radiation therapy for bulky masses.

Authors:  Damodar Pokhrel; Mark E Bernard; Richard Mallory; William St Clair; Mahesh Kudrimoti
Journal:  J Appl Clin Med Phys       Date:  2022-04-21       Impact factor: 2.243

Review 5.  Radiobiological and Treatment-Related Aspects of Spatially Fractionated Radiotherapy.

Authors:  Leyla Moghaddasi; Paul Reid; Eva Bezak; Loredana G Marcu
Journal:  Int J Mol Sci       Date:  2022-03-20       Impact factor: 5.923

  5 in total

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