| Literature DB >> 23634413 |
Athulya Geetha Asokan1, Sydney D'souza, Jayakumar Jeganathan, Shivananda Pai.
Abstract
Fahr's syndrome refers to a rare syndrome which is characterized by symmetrical and bilateral intracranial calcification. We are presenting a 63 year old male, who complained of progressive dysarthria of 6 months, which was associated with slowness of movements. His neurological examination revealed Parkinsonian features. His CT scan revealed a symmetrical large area of calcification over the basal ganglia, the thalamus and the cerebellum. The secondary causes of the bilateral calcification were ruled out to make the clinical diagnosis of Idiopathic Bilateral Striopallidodentate Calcinosis, which is otherwise called as the Fahr's syndrome. Deposits of calcium and minerals cannot be linked to a single chromosomal locus and further genetic studies are in progress for identifying the chromosomal locus of the disease.Entities:
Keywords: Bilateral intracranial calcification; Fahr’s syndrome
Year: 2013 PMID: 23634413 PMCID: PMC3616573 DOI: 10.7860/JCDR/2013/4946.2814
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X