| Literature DB >> 23634116 |
Guangzhi Shan1, Zhuorong Li, Laixing Hu, Jiandong Jiang, Zongying Liu.
Abstract
In the title compound, C20H19N3O4S, a novel tubulin ligand active against human cancer, the dihedral angle between the pyridine ring and the carbazole ring system is 42.87 (10)°. In the crystal, the mol-ecules are held together by N-H⋯O and C-H⋯O hydrogen bonds into layers, which are assembled into a three-dimensional network via π-π stacking inter-actions between inversion-related pyridine rings, with centroid-centroid distances of 3.5101 (12) Å.Entities:
Year: 2013 PMID: 23634116 PMCID: PMC3629629 DOI: 10.1107/S1600536813007460
Source DB: PubMed Journal: Acta Crystallogr Sect E Struct Rep Online ISSN: 1600-5368