| Literature DB >> 23631004 |
Olga Mayans1, Siegfried Labeit.
Abstract
MuRFs, brief for muscle specific RING finger proteins, correspond to a subfamily of the TRIM/RBCC protein family. Here, we review recent progress on the structural biology of MuRF1, the MuRF family member being most clearly associated with muscle diseases. The emerging understanding of the structural biology of MuRFs and their interaction with their numerous myocellular proteins, at least in part representing ubiquitination targets for MuRFs, is likely to provide future rationales to modulate their activity, thus affecting their roles in muscle disease progression.Entities:
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Year: 2012 PMID： 23631004 DOI： 10.1007/978-1-4614-5398-7_9
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622