Literature DB >> 23629023

Optimization of continuous infusion of piperacillin-tazobactam in children with fever and neutropenia.

Mélanie Delvallée1, Françoise Mazingue, Wadi Abouchahla, Mathilde Delebarre, Frédéric Wallet, René Courcol, Eric Kipnis, Rodrigue Dessein.   

Abstract

The study through Monte Carlo simulation of β-lactam pharmacokinetic/pharmacodynamic target attainment and determination of subsequent serum concentrations of piperacillin-tazobactam administered through continuous infusion to children treated for fever and neutropenia shows that 400 mg/kg/day has the highest probability of target attainment against Pseudomonas aeurginosa in our oncology ward compared with the standard regimen of 300 mg/kg/day.

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Year:  2013        PMID： 23629023     DOI： 10.1097/INF.0b013e318298dfb8

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  5 in total

1.  Population Pharmacokinetics and Safety of Piperacillin-Tazobactam Extended Infusions in Infants and Children.

Authors:  Céline Thibault; Jean Lavigne; Catherine Litalien; Nastya Kassir; Yves Théorêt; Julie Autmizguine
Journal:  Antimicrob Agents Chemother       Date:  2019-10-22       Impact factor: 5.191

2.  A Review of Extended and Continuous Infusion Beta-Lactams in Pediatric Patients.

Authors:  Taylor A Imburgia; Michelle L Kussin
Journal:  J Pediatr Pharmacol Ther       Date:  2022-03-21

3.  Piperacillin Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children with Normal and Augmented Renal Clearance.

Authors:  Agathe Béranger; Sihem Benaboud; Saïk Urien; Florence Moulin; Emmanuelle Bille; Fabrice Lesage; Yi Zheng; Mathieu Genuini; Inès Gana; Sylvain Renolleau; Déborah Hirt; Jean-Marc Tréluyer; Mehdi Oualha
Journal:  Clin Pharmacokinet       Date:  2019-02       Impact factor: 6.447

4.  Population Pharmacokinetics and Pharmacodynamics of Extended-Infusion Piperacillin and Tazobactam in Critically Ill Children.

Authors:  Kristen Nichols; Eun Kyoung Chung; Chad A Knoderer; Lauren E Buenger; Daniel P Healy; Jennifer Dees; Ashley S Crumby; Michael B Kays
Journal:  Antimicrob Agents Chemother       Date:  2015-11-09       Impact factor: 5.191

5.  Continuous infusion of piperacillin-tazobactam significantly improves target attainment in children with cancer and fever.

Authors:  Sabine F Maarbjerg; Anders Thorsted; Lena E Friberg; Elisabet I Nielsen; Mikala Wang; Henrik Schrøder; Birgitte K Albertsen
Journal:  Cancer Rep (Hoboken)       Date:  2021-11-18
  5 in total

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