Literature DB >> 23628938

Multivalent alteration of quorum sensing in Staphylococcus aureus.

Sarit Melamed Yerushalmi1, Maren E Buck, David M Lynn, N Gabriel Lemcoff, Michael M Meijler.   

Abstract

Virulence in Staphylococcus aureus is strongly and positively correlated with local cell density. Here we present an effective approach to modulate this group behaviour using multivalent peptide-polymer conjugates. Our results show that by attaching multiple AIP-4' units to macromolecular scaffolds, the agr QS response in S. aureus was affected strongly, while displaying a clear multivalency effect.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23628938     DOI： 10.1039/c3cc41645c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Simplified Autoinducing Peptide Mimetics with Single-Nanomolar Activity Against the Staphylococcus aureus AgrC Quorum Sensing Receptor.

Authors:  Joseph K Vasquez; Helen E Blackwell
Journal:  ACS Infect Dis       Date:  2019-03-13       Impact factor: 5.084

Review 2.  Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections.

Authors:  Burhan A Khan; Anthony J Yeh; Gordon Y C Cheung; Michael Otto
Journal:  Expert Opin Investig Drugs       Date:  2015-02-23       Impact factor: 6.206

3.  Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles.

Authors:  Hoang D Lu; Alina C Spiegel; Amanda Hurley; Lark J Perez; Katharina Maisel; Laura M Ensign; Justin Hanes; Bonnie L Bassler; Martin F Semmelhack; Robert K Prud'homme
Journal:  Nano Lett       Date:  2015-03-03       Impact factor: 11.189

4.  Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus.

Authors:  Yftah Tal-Gan; Monika Ivancic; Gabriel Cornilescu; Helen E Blackwell
Journal:  Org Biomol Chem       Date:  2015-09-29       Impact factor: 3.876

5.  Cellulose Nanocrystal Membranes as Excipients for Drug Delivery Systems.

Authors:  Ananda M Barbosa; Eduardo Robles; Juliana S Ribeiro; Rafael G Lund; Neftali L V Carreño; Jalel Labidi
Journal:  Materials (Basel)       Date:  2016-12-12       Impact factor: 3.623

6.  Cross-kingdom inhibition of bacterial virulence and communication by probiotic yeast metabolites.

Authors:  Orit Malka; Dorin Kalson; Karin Yaniv; Reut Shafir; Manikandan Rajendran; Oshrit Ben-David; Ariel Kushmaro; Michael M Meijler; Raz Jelinek
Journal:  Microbiome       Date:  2021-03-24       Impact factor: 14.650

7.  Transcriptional downregulation of agr expression in Staphylococcus aureus during growth in human serum can be overcome by constitutively active mutant forms of the sensor kinase AgrC.

Authors:  Ellen H James; Andrew M Edwards; Sivaramesh Wigneshweraraj
Journal:  FEMS Microbiol Lett       Date:  2013-11-18       Impact factor: 2.742

Review 8.  Quorum-sensing regulation in staphylococci-an overview.

Authors:  Katherine Y Le; Michael Otto
Journal:  Front Microbiol       Date:  2015-10-27       Impact factor: 5.640
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.