Literature DB >> 23627998

Determinants of clinical right ventricular failure after congenital heart surgery in adults.

Mark J Schuuring1, E Charlotte van Gulik, Dave R Koolbergen, Mark G Hazekamp, Wim K Lagrand, Ad P C M Backx, Barbara J M Mulder, Berto J Bouma.   

Abstract

OBJECTIVES: Right ventricular (RV) failure after cardiac surgery is a clinical entity with high morbidity and mortality. Patients with congenital heart disease (CHD) often undergo right-sided cardiac surgery. The authors aimed to identify determinants of RV failure after cardiac surgery to differentiate patients with increased risk.
DESIGN: A retrospective chart review.
SETTING: University hospital. PARTICIPANTS: Adults with CHD operated on between January 2001 and January 2011.
INTERVENTIONS: Clinical characteristics, laboratory tests, surgical data, and intensive care unit outcome were obtained from medical records.
MEASUREMENTS AND MAIN RESULTS: The diagnosis of clinical RV failure was made by careful review of the medical records by 2 independent physicians. Patients only were identified as having RV failure if (1) they had elevated jugular venous pressure, (2) they had impaired postoperative RV function on transthoracic echocardiography, and (3) a diagnosis of RV failure was documented clearly in the medical charts by the treating physician. Data of 412 consecutive patients (median age 36 [range 18-74] years, 56% male) were studied. Eighteen patients had clinical RV failure (4.4%) postoperatively, of whom 6 patients died. Patients undergoing left- and both-sided surgery had an equal risk of developing clinical RV failure as compared with patients undergoing right-sided surgery. In multivariate logistic regression analysis, preoperative impaired RV function, supraventricular tachycardia, and cardiopulmonary bypass time >150 minutes were the strongest determinants of clinical RV failure (p<0.05, for all).
CONCLUSIONS: RV failure after cardiac surgery is a serious complication, and occurs regardless of the side of surgery. A tailored approach in patients with CHD at highest risk of RV failure should be considered.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  adult CHD; cardiac surgery; congenital heart disease; right ventricular failure

Mesh:

Substances:

Year:  2013        PMID: 23627998     DOI: 10.1053/j.jvca.2012.10.022

Source DB:  PubMed          Journal:  J Cardiothorac Vasc Anesth        ISSN: 1053-0770            Impact factor:   2.628


  6 in total

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Authors:  Stephen J Huang; Marek Nalos; Louise Smith; Arvind Rajamani; Anthony S McLean
Journal:  Intensive Care Med       Date:  2018-05-22       Impact factor: 17.440

2.  Critical care management of the adult patient with congenital heart disease: focus on postoperative management and outcomes.

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Journal:  Curr Treat Options Cardiovasc Med       Date:  2015-02

3.  Mobile health in adults with congenital heart disease: current use and future needs.

Authors:  M J Schuuring; A P Backx; R Zwart; A H Veelenturf; D Robbers-Visser; M Groenink; A Abu-Hanna; N Bruining; M P Schijven; B J Mulder; B J Bouma
Journal:  Neth Heart J       Date:  2016-11       Impact factor: 2.380

Review 4.  Postoperative Right Ventricular Failure in Cardiac Surgery.

Authors:  Victor H Nieto Estrada; Daniel L Molano Franco; Albert A Valencia Moreno; Jose A Rojas Gambasica; Cristian C Cortes Nunez
Journal:  Cardiol Res       Date:  2016-12-31

Review 5.  A standardized definition for right ventricular failure in cardiac surgery patients.

Authors:  Habib Jabagi; Alex Nantsios; Marc Ruel; Lisa M Mielniczuk; André Y Denault; Louise Y Sun
Journal:  ESC Heart Fail       Date:  2022-03-09

6.  Prophylactic Right Ventricular Assist Device for High-Risk Patients Undergoing Valve Corrective Surgery.

Authors:  Atul Jaidka; Sabe De; A Dave Nagpal; Michael W A Chu
Journal:  CJC Open       Date:  2019-01-23
  6 in total

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