Literature DB >> 23626007

Gene of the month: KRAS.

Runjan Chetty1, Dhirendra Govender.   

Abstract

This is a general overview of KRAS, its structure and role in pertinent cancers. Also its role in determining adjuvant therapy is discussed.

Entities:  

Keywords:  Cancer; Genetics; Molecular pathology

Mesh：

Substances：

Year:  2013        PMID： 23626007     DOI： 10.1136/jclinpath-2013-201663

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  15 in total

1.  Dual Farnesyl and Geranylgeranyl Transferase Inhibitor Thwarts Mutant KRAS-Driven Patient-Derived Pancreatic Tumors.

Authors:  Aslamuzzaman Kazi; Shengyan Xiang; Hua Yang; Liwei Chen; Perry Kennedy; Muhammad Ayaz; Steven Fletcher; Christopher Cummings; Harshani R Lawrence; Francisca Beato; Ya'an Kang; Michael P Kim; Andrea Delitto; Patrick W Underwood; Jason B Fleming; Jose G Trevino; Andrew D Hamilton; Said M Sebti
Journal:  Clin Cancer Res       Date:  2019-06-21       Impact factor: 12.531

2.  KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells.

Authors:  Dominic Leiser; Michaela Medová; Kei Mikami; Lluís Nisa; Deborah Stroka; Andree Blaukat; Friedhelm Bladt; Daniel M Aebersold; Yitzhak Zimmer
Journal:  Mol Oncol       Date:  2015-04-14       Impact factor: 6.603

Review 3.  Noncoding RNA and colorectal cancer: its epigenetic role.

Authors:  Yoshiaki Kita; Keiichi Yonemori; Yusaku Osako; Kenji Baba; Shinichiro Mori; Kosei Maemura; Shoji Natsugoe
Journal:  J Hum Genet       Date:  2016-06-09       Impact factor: 3.172

Review 4.  Ovarian cancer in endometriosis: clinical and molecular aspects.

Authors:  B Lyttle; L Bernardi; M E Pavone
Journal:  Minerva Ginecol       Date:  2014-04

5.  Medullary carcinoma of the colon: can the undifferentiated be differentiated?

Authors:  Anne-Marie Kanstrup Fiehn; Morten Grauslund; Anders Glenthøj; Linea Cecilie Melchior; Ben Vainer; Gro Linno Willemoe
Journal:  Virchows Arch       Date:  2014-10-23       Impact factor: 4.064

6.  Molecularly targeted therapies in non-small-cell lung cancer annual update 2014.

Authors:  Daniel Morgensztern; Meghan J Campo; Suzanne E Dahlberg; Robert C Doebele; Edward Garon; David E Gerber; Sarah B Goldberg; Peter S Hammerman; Rebecca S Heist; Thomas Hensing; Leora Horn; Suresh S Ramalingam; Charles M Rudin; Ravi Salgia; Lecia V Sequist; Alice T Shaw; George R Simon; Neeta Somaiah; David R Spigel; John Wrangle; David Johnson; Roy S Herbst; Paul Bunn; Ramaswamy Govindan
Journal:  J Thorac Oncol       Date:  2015-01       Impact factor: 15.609

Review 7.  The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer.

Authors:  Sunny Guin; Dan Theodorescu
Journal:  Acta Pharmacol Sin       Date:  2015-01-05       Impact factor: 6.150

Review 8.  Non-coding landscapes of colorectal cancer.

Authors:  Marco Ragusa; Cristina Barbagallo; Luisa Statello; Angelo Giuseppe Condorelli; Rosalia Battaglia; Lucia Tamburello; Davide Barbagallo; Cinzia Di Pietro; Michele Purrello
Journal:  World J Gastroenterol       Date:  2015-11-07       Impact factor: 5.742

9.  Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer.

Authors:  Aslamuzzaman Kazi; Liwei Chen; Shengyan Xiang; Rajanikanth Vangipurapu; Hua Yang; Francisca Beato; Bin Fang; Terence M Williams; Kazim Husain; Patrick Underwood; Jason B Fleming; Mokenge Malafa; Eric A Welsh; John Koomen; José Trevino; Saïd M Sebti
Journal:  Clin Cancer Res       Date:  2021-04-20       Impact factor: 12.531

Review 10.  Endometriosis and ovarian cancer: links, risks, and challenges faced.

Authors:  Mary Ellen Pavone; Brianna M Lyttle
Journal:  Int J Womens Health       Date:  2015-07-01
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