Literature DB >> 23625840

Goodness-of-fit test for proportional subdistribution hazards model.

Bingqing Zhou1, Jason Fine, Glen Laird.   

Abstract

This paper concerns using modified weighted Schoenfeld residuals to test the proportionality of subdistribution hazards for the Fine-Gray model, similar to the tests proposed by Grambsch and Therneau for independently censored data. We develop a score test for the time-varying coefficients based on the modified Schoenfeld residuals derived assuming a certain form of non-proportionality. The methods perform well in simulations and a real data analysis of breast cancer data, where the treatment effect exhibits non-proportional hazards.
Copyright © 2013 John Wiley & Sons, Ltd.

Entities:  

Keywords:  Martingale residual; competing risk; goodness-of-fit; hazard of subdistribution; proportional hazard; score test

Mesh:

Substances:

Year:  2013        PMID: 23625840     DOI: 10.1002/sim.5815

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  21 in total

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