| Literature DB >> 23625840 |
Bingqing Zhou1, Jason Fine, Glen Laird.
Abstract
This paper concerns using modified weighted Schoenfeld residuals to test the proportionality of subdistribution hazards for the Fine-Gray model, similar to the tests proposed by Grambsch and Therneau for independently censored data. We develop a score test for the time-varying coefficients based on the modified Schoenfeld residuals derived assuming a certain form of non-proportionality. The methods perform well in simulations and a real data analysis of breast cancer data, where the treatment effect exhibits non-proportional hazards.Entities:
Keywords: Martingale residual; competing risk; goodness-of-fit; hazard of subdistribution; proportional hazard; score test
Mesh:
Substances:
Year: 2013 PMID: 23625840 DOI: 10.1002/sim.5815
Source DB: PubMed Journal: Stat Med ISSN: 0277-6715 Impact factor: 2.373