BACKGROUND: Cluster headache (CH) is a primary headache disorder that is diagnosed based on the patient's history. For large-scale epidemiologic and genetic studies, a web-based, preferably short, questionnaire can be a feasible alternative to replace time-consuming clinical interviews. METHODS: Self-reported CH patients were enrolled via our research website. Participants meeting screening criteria were directed to the Leiden University Cluster headache Analysis program (LUCA) questionnaire. Individual diagnoses were calculated using an algorithm based on International Headache Society criteria. Subsequently, semi-structured telephone interviews were carried out to validate the LUCA questionnaire. The shorter Quick Ascertainment of Cluster Headache (QATCH) questionnaire for diagnosing CH was constructed by using logistic regression to select the most predictive questions. RESULTS: Via our website 437 self-reported CH patients were recruited. Of these, 291 patients were included in this cross-sectional study. The LUCA questionnaire was valid and accurate. Using logistic regression, three questions (QATCH) provided similar sensitivity (53.8% vs. 57.2%), specificity (88.9% vs. 87.5%), positive predictive value (95.5% vs. 95.9%) and negative predictive value (30.8% vs. 28.8%) compared with the LUCA questionnaire. CONCLUSION: The web-based LUCA questionnaire was accurate and reliable in diagnosing CH among self-reported patients. Males with headache attacks of short duration and long headache-free intervals (months to years) are very likely to have CH.
BACKGROUND:Cluster headache (CH) is a primary headache disorder that is diagnosed based on the patient's history. For large-scale epidemiologic and genetic studies, a web-based, preferably short, questionnaire can be a feasible alternative to replace time-consuming clinical interviews. METHODS: Self-reported CH patients were enrolled via our research website. Participants meeting screening criteria were directed to the Leiden University Cluster headache Analysis program (LUCA) questionnaire. Individual diagnoses were calculated using an algorithm based on International Headache Society criteria. Subsequently, semi-structured telephone interviews were carried out to validate the LUCA questionnaire. The shorter Quick Ascertainment of Cluster Headache (QATCH) questionnaire for diagnosing CH was constructed by using logistic regression to select the most predictive questions. RESULTS: Via our website 437 self-reported CH patients were recruited. Of these, 291 patients were included in this cross-sectional study. The LUCA questionnaire was valid and accurate. Using logistic regression, three questions (QATCH) provided similar sensitivity (53.8% vs. 57.2%), specificity (88.9% vs. 87.5%), positive predictive value (95.5% vs. 95.9%) and negative predictive value (30.8% vs. 28.8%) compared with the LUCA questionnaire. CONCLUSION: The web-based LUCA questionnaire was accurate and reliable in diagnosing CH among self-reported patients. Males with headache attacks of short duration and long headache-free intervals (months to years) are very likely to have CH.
Authors: Else Eising; Nadine Pelzer; Lisanne S Vijfhuizen; Boukje de Vries; Michel D Ferrari; Peter A C 't Hoen; Gisela M Terwindt; Arn M J M van den Maagdenberg Journal: Sci Rep Date: 2017-01-11 Impact factor: 4.379
Authors: Ilse F de Coo; Willebrordus P J van Oosterhout; Leopoldine A Wilbrink; Erik W van Zwet; Michel D Ferrari; Rolf Fronczek Journal: Headache Date: 2019-05-31 Impact factor: 5.887
Authors: Ilse F de Coo; Willemijn C Naber; Leopoldine A Wilbrink; Joost Haan; Michel D Ferrari; Rolf Fronczek Journal: Cephalalgia Date: 2018-10-05 Impact factor: 6.292
Authors: Randika Parakramaweera; Randolph W Evans; Larry I Schor; Stuart M Pearson; Rebecca Martinez; Jacob S Cammarata; Amisha J Amin; Seung-Hee Yoo; Wei Zhang; Yuanqing Yan; Mark J Burish Journal: Cephalalgia Date: 2021-06-20 Impact factor: 6.292