Literature DB >> 23623803

Molecular characterization of carbapenem-resistant Klebsiella pneumoniae in a tertiary university hospital in Turkey.

E Alp1, D Perçin, S Colakoğlu, S Durmaz, C A Kürkcü, P Ekincioğlu, T Güneş.   

Abstract

The aim of this study was to identify the resistance genes and genetic relationship of carbapenemase-resistant Klebsiella pneumoniae (CRKP) identified in a tertiary university hospital in Turkey. During the study, CRKP was isolated from 137 patients. Resistance genes were studied in 94 isolates. Among these isolates, most of the CRKP produced only oxacillinase (OXA)-48 (91.5%); however, 4.3% of the isolates produced only New Delhi metallo-beta-lactamase 1 (NDM-1), 1% produced both OXA-48 and NDM-1, and 3.2% produced imipenem. This study adds Turkey to the growing list of countries with NDM-1-producing bacteria and shows that NDM-1 may easily spread worldwide.
Copyright © 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23623803     DOI: 10.1016/j.jhin.2013.03.002

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  22 in total

1.  Evaluation of a new chromogenic medium, chromID OXA-48, for recovery of carbapenemase-producing Enterobacteriaceae from patients at a university hospital in Turkey.

Authors:  P Zarakolu; K M Day; H E Sidjabat; W Kamolvit; C V Lanyon; S P Cummings; D L Paterson; M Akova; J D Perry
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-10-12       Impact factor: 3.267

Review 2.  Epidemiology of antimicrobial resistance in bloodstream infections.

Authors:  Murat Akova
Journal:  Virulence       Date:  2016-04-02       Impact factor: 5.882

3.  Investigation of Metallo Beta Lactamases and Oxacilinases in Carbapenem Resistant Acinetobacter baumannii Strains Isolated from Inpatients.

Authors:  M Duygu Aksoy; Şaban Çavuşlu; H Murat Tuğrul
Journal:  Balkan Med J       Date:  2015-01-01       Impact factor: 2.021

Review 4.  Carbapenem-Resistant Gram-Negative Bacterial Infections in Children.

Authors:  David Aguilera-Alonso; Luis Escosa-García; Jesús Saavedra-Lozano; Emilia Cercenado; Fernando Baquero-Artigao
Journal:  Antimicrob Agents Chemother       Date:  2020-02-21       Impact factor: 5.191

5.  Carbapenem-Resistant Enterobacteriaceae Infections in Children.

Authors:  Kathleen Chiotos; Jennifer H Han; Pranita D Tamma
Journal:  Curr Infect Dis Rep       Date:  2016-01       Impact factor: 3.725

6.  Spread of NDM-1-producing Enterobacteriaceae in a neonatal intensive care unit in Istanbul, Turkey.

Authors:  Laurent Poirel; Mesut Yilmaz; Ayse Istanbullu; Ferhat Arslan; Ali Mert; Sandrine Bernabeu; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2014-02-18       Impact factor: 5.191

7.  Outbreak caused by NDM-1- and RmtB-producing Escherichia coli in Bulgaria.

Authors:  Laurent Poirel; Encho Savov; Arzu Nazli; Angelina Trifonova; Iva Todorova; Ivanka Gergova; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2014-02-10       Impact factor: 5.191

8.  In Vitro Activity of Ceftazidime-Avibactam and Aztreonam-Avibactam against OXA-48-Carrying Enterobacteriaceae Isolated as Part of the International Network for Optimal Resistance Monitoring (INFORM) Global Surveillance Program from 2012 to 2015.

Authors:  Krystyna M Kazmierczak; Patricia A Bradford; Gregory G Stone; Boudewijn L M de Jonge; Daniel F Sahm
Journal:  Antimicrob Agents Chemother       Date:  2018-11-26       Impact factor: 5.191

Review 9.  OXA β-lactamases.

Authors:  Benjamin A Evans; Sebastian G B Amyes
Journal:  Clin Microbiol Rev       Date:  2014-04       Impact factor: 26.132

10.  Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing.

Authors:  Yohei Doi; Tracy H Hazen; Matthew Boitano; Yu-Chih Tsai; Tyson A Clark; Jonas Korlach; David A Rasko
Journal:  Antimicrob Agents Chemother       Date:  2014-07-28       Impact factor: 5.191

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