Literature DB >> 23623760

Antidogmatic approaches to artemisinin resistance: reappraisal as treatment failure with artemisinin combination therapy.

Sanjeev Krishna1, Peter Gottfried Kremsner.   

Abstract

The definition of artemisinin resistance is becoming one of a prolonged parasite clearance phenotype, although this variable is a complex function of both host and parasite characteristics. We discuss some of the limitations of this definition of artemisinin resistance, particularly because of its potential global impact. This opinion article reviews the mechanisms underlying parasite clearance after artemisinin treatment and how these might relate to in vitro methods to assay for resistance. It revisits criteria for defining artemisinin resistance that are not currently being applied and suggests the term 'treatment failure of artemisinin combination therapy' (TFACT) as a more accurate description of most cases of 'artemisinin resistance'.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23623760     DOI： 10.1016/j.pt.2013.04.001

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  32 in total

1.  Monitoring artemisinin resistance in Plasmodium falciparum: comparison of parasite clearance time by microscopy and real-time PCR and evaluation of mutations in Pfatpase6 gene in Odisha state of India.

Authors:  Ruchi Gupta; Neelima Mishra; Ashwani Kumar; Roma Rana; Bina Srivastava; P K Tyagi; Anupkumar R Anvikar; Neena Valecha
Journal:  Parasitol Res       Date:  2015-06-27       Impact factor: 2.289

2.  Rocaglates as dual-targeting agents for experimental cerebral malaria.

Authors:  David Langlais; Regina Cencic; Neda Moradin; James M Kennedy; Kodjo Ayi; Lauren E Brown; Ian Crandall; Michael J Tarry; Martin Schmeing; Kevin C Kain; John A Porco; Jerry Pelletier; Philippe Gros
Journal:  Proc Natl Acad Sci U S A       Date:  2018-02-20       Impact factor: 11.205

3.  Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model.

Authors:  Juliana M Sá; Sarah R Kaslow; Michael A Krause; Viviana A Melendez-Muniz; Rebecca E Salzman; Whitney A Kite; Min Zhang; Roberto R Moraes Barros; Jianbing Mu; Paul K Han; J Patrick Mershon; Christine E Figan; Ramoncito L Caleon; Rifat S Rahman; Tyler J Gibson; Chanaki Amaratunga; Erika P Nishiguchi; Kimberly F Breglio; Theresa M Engels; Soundarapandian Velmurugan; Stacy Ricklefs; Judith Straimer; Nina F Gnädig; Bingbing Deng; Anna Liu; Ababacar Diouf; Kazutoyo Miura; Gregory S Tullo; Richard T Eastman; Sumana Chakravarty; Eric R James; Kenneth Udenze; Suzanne Li; Daniel E Sturdevant; Robert W Gwadz; Stephen F Porcella; Carole A Long; David A Fidock; Marvin L Thomas; Michael P Fay; B Kim Lee Sim; Stephen L Hoffman; John H Adams; Rick M Fairhurst; Xin-Zhuan Su; Thomas E Wellems
Journal:  Proc Natl Acad Sci U S A       Date:  2018-11-19       Impact factor: 11.205

4.  Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort.

Authors:  Ricardo Ataide; Elizabeth A Ashley; Rosanna Powell; Jo-Anne Chan; Michael J Malloy; Katherine O'Flaherty; Eizo Takashima; Christine Langer; Takafumi Tsuboi; Arjen M Dondorp; Nicholas P Day; Mehul Dhorda; Rick M Fairhurst; Pharath Lim; Chanaki Amaratunga; Sasithon Pukrittayakamee; Tran Tinh Hien; Ye Htut; Mayfong Mayxay; M Abul Faiz; James G Beeson; Francois Nosten; Julie A Simpson; Nicholas J White; Freya J I Fowkes
Journal:  Proc Natl Acad Sci U S A       Date:  2017-03-13       Impact factor: 11.205

5.  Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness.

Authors:  Katherine Kay; Eva Maria Hodel; Ian M Hastings
Journal:  Antimicrob Agents Chemother       Date:  2015-08-03       Impact factor: 5.191

6.  How Robust Are Malaria Parasite Clearance Rates as Indicators of Drug Effectiveness and Resistance?

Authors:  Ian M Hastings; Katherine Kay; Eva Maria Hodel
Journal:  Antimicrob Agents Chemother       Date:  2015-08-03       Impact factor: 5.191

7.  Selective Inhibition of Plasmodium falciparum ATPase 6 by Artemisinins and Identification of New Classes of Inhibitors after Expression in Yeast.

Authors:  Catherine M Moore; Jigang Wang; Qingsong Lin; Pedro Ferreira; Mitchell A Avery; Khaled Elokely; Henry M Staines; Sanjeev Krishna
Journal:  Antimicrob Agents Chemother       Date:  2022-04-25       Impact factor: 5.938

8.  Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring.

Authors:  Laura C Pollitt; Derek Sim; Rahel Salathé; Andrew F Read
Journal:  Evol Appl       Date:  2014-08-11       Impact factor: 5.183

9.  Characterization and optimization of the haemozoin-like crystal (HLC) assay to determine Hz inhibiting effects of anti-malarial compounds.

Authors:  Carolina Tempera; Ricardo Franco; Carlos Caro; Vânia André; Peter Eaton; Peter Burke; Thomas Hänscheid
Journal:  Malar J       Date:  2015-10-12       Impact factor: 2.979

10.  Four years' monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border.

Authors:  Papichaya Phompradit; Poonuch Muhamad; Raewadee Wisedpanichkij; Wanna Chaijaroenkul; Kesara Na-Bangchang
Journal:  Malar J       Date:  2014-01-15       Impact factor: 2.979
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.