Literature DB >> 23623450

Polymorphisms in schizophrenia candidate gene UFD1L may contribute to cognitive deficits.

Vanessa K Ota1, Arthur A Berberian, Ary Gadelha, Marcos L Santoro, Gustavo L Ottoni, Camila T Matsuzaka, Jair J Mari, Maria I Melaragno, Diogo R Lara, Marília A C Smith, Sintia I Belangero, Rodrigo A Bressan.   

Abstract

We aimed to investigate UFD1L polymorphisms in schizophrenia and in relation to cognition. A total of 299 cases and 363 controls were genotyped, and 130 patients completed nine neuropsychological tests. We found that rs5992403 AA-genotype carriers showed lower scores on the set-shifting task. Therefore, UFD1L may participate in the core cognitive deficits observed in schizophrenia.
Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Cognition; Executive functions; Gene

Mesh：

Substances：

Year:  2013        PMID： 23623450     DOI： 10.1016/j.psychres.2013.03.035

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  4 in total

1.  Accessing Gene Expression in Treatment-Resistant Schizophrenia.

Authors:  Patricia N Moretti; Vanessa K Ota; Eduardo S Gouvea; Mariana Pedrini; Marcos L Santoro; Fernanda Talarico; Leticia M Spindola; Carolina Muniz Carvalho; Cristiano Noto; Gabriela Xavier; Elisa Brietzke; Ary Gadelha; Rodrigo Bressan; Jair Mari; Sintia Belangero
Journal:  Mol Neurobiol       Date:  2018-01-26       Impact factor: 5.590

2.  Association of genetic variants at 22q11.2 chromosomal region with cognitive performance in Japanese patients with schizophrenia.

Authors:  Kazufumi Akiyama; Atsushi Saito; Satoshi Saito; Yuji Ozeki; Takashi Watanabe; Kumiko Fujii; Kazutaka Shimoda
Journal:  Schizophr Res Cogn       Date:  2019-03-26

3.  Component mechanisms of executive function in schizophrenia and their contribution to functional outcomes.

Authors:  Arthur A Berberian; Ary Gadelha; Natália M Dias; Tatiana P Mecca; William E Comfort; Rodrigo A Bressan; Acioly T Lacerda
Journal:  Braz J Psychiatry       Date:  2018-10-22       Impact factor: 2.697

4.  Is semantic verbal fluency impairment explained by executive function deficits in schizophrenia?

Authors:  Arthur A Berberian; Giovanna V Moraes; Ary Gadelha; Elisa Brietzke; Ana O Fonseca; Bruno S Scarpato; Marcella O Vicente; Alessandra G Seabra; Rodrigo A Bressan; Acioly L Lacerda
Journal:  Braz J Psychiatry       Date:  2016-04-19       Impact factor: 2.697
  4 in total

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