OBJECTIVES: To assess long-term efficacy of the collagen-only biomatrix as a dural substitute in a large case series. PATIENTS AND METHODS: We reviewed a prospectively acquired database of patients who underwent neurosurgical surgeries in whom the dural substitute was used and who were the subject of two previous studied with shorter follow-ups. RESULTS: The present study was conducted on 111 subjects of the original 209 patients. No late complications, nor local or systemic toxicity were observed during the observational period. As a matter of facts, 5 patients (4.5%) underwent reoperation for different reasons and 2 out of 5 experienced subcutaneous fluid collections; another case (0.9%), already reported in our previous studies, developed a CSF leak after an endoscopic endonasal operation for an intra-suprasellar arachnoid cyst. CONCLUSIONS: Our data further confirm that the collagen-only biomatrix derived from horse equine tendon is a safe and effective dural substitute for routine neurosurgical procedures.
OBJECTIVES: To assess long-term efficacy of the collagen-only biomatrix as a dural substitute in a large case series. PATIENTS AND METHODS: We reviewed a prospectively acquired database of patients who underwent neurosurgical surgeries in whom the dural substitute was used and who were the subject of two previous studied with shorter follow-ups. RESULTS: The present study was conducted on 111 subjects of the original 209 patients. No late complications, nor local or systemic toxicity were observed during the observational period. As a matter of facts, 5 patients (4.5%) underwent reoperation for different reasons and 2 out of 5 experienced subcutaneous fluid collections; another case (0.9%), already reported in our previous studies, developed a CSF leak after an endoscopic endonasal operation for an intra-suprasellar arachnoid cyst. CONCLUSIONS: Our data further confirm that the collagen-only biomatrix derived from horseequine tendon is a safe and effective dural substitute for routine neurosurgical procedures.
Authors: M Pogorielov; A Kravtsova; G C Reilly; V Deineka; G Tetteh; O Kalinkevich; O Pogorielova; R Moskalenko; G Tkach Journal: J Mater Sci Mater Med Date: 2017-01-21 Impact factor: 3.896
Authors: Ahmet Kinaci; Wilhelmina Bergmann; Ronald Law Bleys; Albert van der Zwan; Tristan Pc van Doormaal Journal: Comp Med Date: 2020-02-03 Impact factor: 0.982
Authors: Felice Esposito; Filippo Flavio Angileri; Peter Kruse; Luigi Maria Cavallo; Domenico Solari; Vincenzo Esposito; Francesco Tomasello; Paolo Cappabianca Journal: PLoS One Date: 2016-04-27 Impact factor: 3.240
Authors: Kevin M Lewis; Jenifer Sweet; Scott T Wilson; Serge Rousselle; Heinz Gulle; Bernhard Baumgartner Journal: Neurosurgery Date: 2018-03-01 Impact factor: 4.654