Literature DB >> 23622006

Outcomes of stepping down asthma medications in a guideline-based pediatric asthma management program.

Matthew A Rank1, Megan E Branda, Deborah B McWilliams, Shirley K Johnson, Shefali A Samant, Jenna C Podjasek, Miguel A Park, Gerald W Volcheck.   

Abstract

BACKGROUND: Little is known about outcomes after stepping down asthma medications within an asthma management program.
OBJECTIVE: To determine outcomes of stepping down asthma medications in a pediatric asthma management program.
METHODS: We performed a retrospective study of 5- to 18-year-old children with asthma in an integrated primary care practice in the United States. Data were included on participants from March 1, 2009, until December 31, 2011. We first determined whether a child was eligible for step down and next recorded whether a step-down attempt was made and if the attempt was successful. In addition to descriptive statistics for the sample demographics and the outcomes of stepping down, univariate and multivariate analyses were performed to determine predictors of successful asthma medication step-down attempts.
RESULTS: Of the 477 children sampled for this study, 264 (55.3%) had a guideline-eligible opportunity to step down asthma medications. An attempted step down occurred in only 89 (33.7%) of children who had guideline-eligible opportunities. A total of 166 children (34.8%) attempted a step down of asthma medication at least once (including those guideline ineligible to step down). Of children with follow-up, 96 (71.6%) of step-down attempts were successful. Time of year (any season except fall) when the step down was attempted predicted successful step down in univariate and multivariate analysis (odds ratio = 3.81; 95% confidence interval, 1.23-11.85; P = .02). Being guideline eligible for step down predicted successful step down in univariate analysis only (odds ratio = 2.51; 95% confidence interval, 1.16-5.43; P = .02).
CONCLUSION: Our findings from this sample of children participating in an asthma management program suggest that stepping down asthma medication based on National Asthma Education and Prevention Program 3 guidelines is frequently successful.
Copyright © 2013 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 23622006     DOI: 10.1016/j.anai.2013.02.012

Source DB:  PubMed          Journal:  Ann Allergy Asthma Immunol        ISSN: 1081-1206            Impact factor:   6.347


  5 in total

Review 1.  Assessing the risks and benefits of step-down asthma care: a case-based approach.

Authors:  John B Hagan; Matthew A Rank
Journal:  Curr Allergy Asthma Rep       Date:  2015-04       Impact factor: 4.806

Review 2.  Stepping down inhaled corticosteroids from scheduled to as needed in stable asthma: Systematic review and meta-analysis.

Authors:  Michael R Gionfriddo; John B Hagan; Christina R Hagan; Gerald W Volcheck; Ana Castaneda-Guarderas; Matthew A Rank
Journal:  Allergy Asthma Proc       Date:  2015 Jul-Aug       Impact factor: 2.587

3.  Advances in pediatric asthma in 2013: coordinating asthma care.

Authors:  Stanley J Szefler
Journal:  J Allergy Clin Immunol       Date:  2014-03       Impact factor: 10.793

4.  Development and validation of a predictive model of failed stepping-down of inhaled corticosteroids in adult asthmatics.

Authors:  Akira Yamasaki; Katsuyuki Tomita; Kazuhiro Kato; Kouji Fukutani; Hiroyuki Sano; Yuji Tohda; Eiji Shimizu
Journal:  Patient Prefer Adherence       Date:  2016-03-18       Impact factor: 2.711

5.  Shared Care for Patients with Diabetes at Risk of Retinopathy: A Feasibility Trial.

Authors:  Ranjana Mathur; Dirk F de Korne; Tien Yin Wong; Donald Tan Tiang Hwee; Peggy P Chiang; Edmund Wong; Bibhas Chakraborty; Ecosse L Lamoureux
Journal:  Int J Integr Care       Date:  2019-09-18       Impact factor: 5.120

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.