Literature DB >> 23621763

Synthesis of 2-aminophenols and heterocycles by Ru-catalyzed C-H mono- and dihydroxylation.

Xinglin Yang1, Gang Shan, Yu Rao.   

Abstract

A novel and efficient synthesis of 2-aminophenols, 2-aminobenzene-1,3-diols, and heterocycles through Ru-catalyzed C-H mono- and dihydroxylation of anilides has been developed with a new directing group strategy. The reaction demonstrates excellent reactivity, regioselectivity, good functional group tolerance, and high yields.

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Year:  2013        PMID： 23621763     DOI： 10.1021/ol400437a

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  10 in total

1.  Total Synthesis of (-)-Kopsifoline A and (+)-Kopsifoline E.

Authors:  In-Soo Myeong; Nadide Hazal Avci; Mohammad Movassaghi
Journal:  Org Lett       Date:  2021-11-12       Impact factor: 6.072

2.  Concise Total Syntheses of (+)-Haplocidine and (+)-Haplocine via Late-Stage Oxidation of (+)-Fendleridine Derivatives.

Authors:  Kolby L White; Mohammad Movassaghi
Journal:  J Am Chem Soc       Date:  2016-08-26       Impact factor: 15.419

3.  Palladium-catalyzed hydroxylation of aryl and heteroaryl halides enabled by the use of a palladacycle precatalyst.

Authors:  Chi Wai Cheung; Stephen L Buchwald
Journal:  J Org Chem       Date:  2014-05-06       Impact factor: 4.354

4.  A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis.

Authors:  Feng Xiong; Liang Lu; Tian-Yu Sun; Qian Wu; Dingyuan Yan; Ying Chen; Xinhao Zhang; Wei Wei; Yi Lu; Wei-Yin Sun; Jie Jack Li; Jing Zhao
Journal:  Nat Commun       Date:  2017-06-19       Impact factor: 14.919

Review 5.  Transition-metal-catalyzed synthesis of phenols and aryl thiols.

Authors:  Yajun Liu; Shasha Liu; Yan Xiao
Journal:  Beilstein J Org Chem       Date:  2017-03-23       Impact factor: 2.883

6.  A redox-neutral catechol synthesis.

Authors:  Qian Wu; Dingyuan Yan; Ying Chen; Ting Wang; Feng Xiong; Wei Wei; Yi Lu; Wei-Yin Sun; Jie Jack Li; Jing Zhao
Journal:  Nat Commun       Date:  2017-01-27       Impact factor: 14.919

7.  A diversity-oriented synthesis of bioactive benzanilides via a regioselective C(sp2)-H hydroxylation strategy.

Authors:  Yong-Hui Sun; Tian-Yu Sun; Yun-Dong Wu; Xinhao Zhang; Yu Rao
Journal:  Chem Sci       Date:  2015-12-03       Impact factor: 9.825

8.  Synthesis and conversion of primary and secondary 2-aminoestradiols into A-ring-integrated benzoxazolone hybrids and their in vitro anticancer activity.

Authors:  Ferenc Kovács; Mohana K Gopisetty; Dóra I Adamecz; Mónika Kiricsi; Éva A Enyedy; Éva Frank
Journal:  RSC Adv       Date:  2021-04-14       Impact factor: 3.361

9.  Synthesis of 4-Hydroxycarbazole Derivatives by Benzannulation of 3-Nitroindoles with Alkylidene Azlactones.

Authors:  Dongdong Cao; Gang Chen; Dingben Chen; Zhijun Xia; Zongyang Li; Yi Wang; Dongqing Xu; Jianguo Yang
Journal:  ACS Omega       Date:  2021-06-25

10.  Identification of monodentate oxazoline as a ligand for copper-promoted ortho-C-H hydroxylation and amination.

Authors:  Ming Shang; Qian Shao; Shang-Zheng Sun; Yan-Qiao Chen; Hui Xu; Hui-Xiong Dai; Jin-Quan Yu
Journal:  Chem Sci       Date:  2016-09-26       Impact factor: 9.825
  10 in total

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