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Literature DB >> 23618685

Telomeres in lung disease.

Abstract

Telomeres are DNA-protein structures that cap the ends of chromosomes; telomerase is the enzyme that ensures their integrity. Telomere biology has recently been implicated in the pathogenesis of a variety of lung diseases, including idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease/emphysema, and lung cancer. This review highlights recent discoveries pertaining to the role of telomere biology in lung disease.

Entities: Disease

Keywords: COPD; IPF; TERC; TERT; chronic obstructive pulmonary disease; idiopathic pulmonary fibrosis; telomerase RNA component; telomerase reverse transcriptase

Mesh：

Substances：
Telomerase

Year: 2013 PMID： 23618685 DOI： 10.1016/j.trsl.2013.04.001

Source DB: PubMed Journal: Transl Res ISSN： 1878-1810 Impact factor: 7.012

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Cited

16 in total

Review 1. Interstitial lung disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.

Authors: Ivan O Rosas; Paul F Dellaripa; David J Lederer; Dinesh Khanna; Lisa R Young; Fernando J Martinez
Journal: Ann Am Thorac Soc Date: 2014-04

2. Peripheral blood telomere alterations in ground glass opacity (GGO) lesions may suggest malignancy.

Authors: Matthew Koslow; David Shitrit; Lilach Israeli-Shani; Orit Uziel; Einat Beery; Alexandra Osadchy; Yael Refaely; Gali Epstein Shochet; Aliza Amiel
Journal: Thorac Cancer Date: 2019-03-12 Impact factor: 3.500

3. Pregnancy outcomes in inherited bone marrow failure syndromes.

Authors: John M Gansner; Maureen M Achebe; Kathryn J Gray; Revital Yefidoff-Freedman; Elena Labovitis; Aric Parnes; Jean M Connors; Nathan T Connell; Marie N Discenza; Robert I Handin; Nancy Berliner; Akiko Shimamura; Elizabeth S Ginsburg; Nicole A Smith
Journal: Blood Date: 2017-08-10 Impact factor: 22.113

Review 4. Diseases of pulmonary surfactant homeostasis.

Authors: Jeffrey A Whitsett; Susan E Wert; Timothy E Weaver
Journal: Annu Rev Pathol Date: 2015 Impact factor: 23.472

5. Does Telomere Length Indicate Biological, Physical, and Cognitive Health Among Older Adults? Evidence from the Health and Retirement Study.

Authors: Lauren L Brown; Yuan S Zhang; Colter Mitchell; Jennifer Ailshire
Journal: J Gerontol A Biol Sci Med Sci Date: 2018-11-10 Impact factor: 6.053

Review 6. Telomere biology and translational research.

Authors: Philip J Mason; Nieves Perdigones
Journal: Transl Res Date: 2013-09-23 Impact factor: 7.012

Review 7. Telomere maintenance and the etiology of adult glioma.

Authors: Kyle M Walsh; John K Wiencke; Daniel H Lachance; Joseph L Wiemels; Annette M Molinaro; Jeanette E Eckel-Passow; Robert B Jenkins; Margaret R Wrensch
Journal: Neuro Oncol Date: 2015-05-25 Impact factor: 12.300

8. Telomere Shortening in Blood Leukocytes of Patients with Chronic Obstructive Pulmonary Disease.

Authors: Makan Sadr; Seyed Mohammad Hossein Noori Mugahi; Gholamreza Hassanzadeh; Seyed Alireza Nadji; Arda Kiani; Atefeh Abedini; Alireza Javadi; Forozan Mohammadi; Mohammad Reza Masjedi; Moslem Bahadori
Journal: Tanaffos Date: 2015

9. Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status.

Authors: Tamara Fernández-Marcelo; Ana Gómez; Irene Pascua; Carmen de Juan; Jacqueline Head; Florentino Hernando; Jose-Ramón Jarabo; Joaquín Calatayud; Antonio-José Torres-García; Pilar Iniesta
Journal: J Exp Clin Cancer Res Date: 2015-08-07

10. Smoking accelerates aging of the small airway epithelium.

Authors: Matthew S Walters; Bishnu P De; Jacqueline Salit; Lauren J Buro-Auriemma; Timothy Wilson; Allison M Rogalski; Lindsay Lief; Neil R Hackett; Michelle R Staudt; Ann E Tilley; Ben-Gary Harvey; Robert J Kaner; Jason G Mezey; Beth Ashbridge; Malcolm A S Moore; Ronald G Crystal
Journal: Respir Res Date: 2014-09-24