| Literature DB >> 23618667 |
Daniel Tianfang Ge1, Phillip D Zamore.
Abstract
Several recent studies demonstrate that piRNAs guide Piwi protein to repress transposon transcription in fly ovaries, much as fission yeast use siRNAs to silence repeat sequences. Still mysterious though is how Piwi targets euchromatic transposons for silencing, but not the specialized heterochromatic loci that produce piRNA precursors.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23618667 DOI: 10.1016/j.cub.2013.03.033
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834