Literature DB >> 23617408

Successful treatment with infliximab for Behçet disease during pregnancy.

Kei Takayama, Sho Ishikawa, Toshio Enoki, Teruo Kojima, Masaru Takeuchi.   

Abstract

PURPOSE: To report a case of successful treatment with infliximab for Behçet disease (BD) during pregnancy.
DESIGN: A case report.
METHODS: A 30-year-old woman was diagnosed with BD at 12 weeks of pregnancy. Additional symptoms occurred, and infliximab at a dose of 5 mg/kg body weight was initiated at 18 weeks and repeated.
RESULTS: All symptoms improved, and a 3950-g infant was delivered uneventfully without any abnormality at 39 weeks. A few weeks after delivery, uveitis and systemic symptoms relapsed. Infliximab was reinitiated and all symptoms were resolved.
CONCLUSIONS: Infliximab may be safe and effective for BD during pregnancy.

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Year:  2013        PMID: 23617408     DOI: 10.3109/09273948.2013.781655

Source DB:  PubMed          Journal:  Ocul Immunol Inflamm        ISSN: 0927-3948            Impact factor:   3.070


  2 in total

Review 1.  Update on the therapy of Behçet disease.

Authors:  Zeinab Saleh; Thurayya Arayssi
Journal:  Ther Adv Chronic Dis       Date:  2014-05       Impact factor: 5.091

Review 2.  [Off-label use of infliximab].

Authors:  M Onder; C Salavastru; K Fritz
Journal:  Hautarzt       Date:  2013-10       Impact factor: 0.751

  2 in total

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