Literature DB >> 23616731

Treating the mother, protecting the unborn: the motherisk approach.

Gideon Koren1.   

Abstract

Pregnant women and their unborn babies are excluded from most pharmaceutical research. We have to convince regulatory agencies worldwide that, by not demanding research of drug safety and effectiveness in pregnancy from pharmaceutical agencies, we are orphaning pregnant women from progress in therapeutics and causing both themselves and their unborn babies tremendous unacceptable risks.

Entities:  

Keywords:  drugs; fetus; knowledge transfer; pregnancy; safety; toxicity

Year:  2013        PMID： 23616731      PMCID： PMC3626065          DOI： 10.5863/1551-6776-18.1.4

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN： 1551-6776


  9 in total

1.  Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother.

Authors:  Gideon Koren; James Cairns; David Chitayat; Andrea Gaedigk; Steven J Leeder
Journal:  Lancet       Date:  2006-08-19       Impact factor: 79.321

2.  Fetal risks of maternal pharmacotherapy: identifying signals.

Authors:  Gideon Koren
Journal:  Handb Exp Pharmacol       Date:  2011

Review 3.  Drugs in pregnancy.

Authors:  G Koren; A Pastuszak; S Ito
Journal:  N Engl J Med       Date:  1998-04-16       Impact factor: 91.245

4.  Neurodevelopment of children exposed in utero to antidepressant drugs.

Authors:  I Nulman; J Rovet; D E Stewart; J Wolpin; H A Gardner; J G Theis; N Kulin; G Koren
Journal:  N Engl J Med       Date:  1997-01-23       Impact factor: 91.245

Review 5.  Novel methods for the detection of drug and alcohol exposure during pregnancy: implications for maternal and child health.

Authors:  G Koren; J Hutson; J Gareri
Journal:  Clin Pharmacol Ther       Date:  2008-02-20       Impact factor: 6.875

6.  Prevalence of fetal ethanol exposure in a regional population-based sample by meconium analysis of fatty acid ethyl esters.

Authors:  Joey Gareri; Hazel Lynn; Maureen Handley; Chitra Rao; Gideon Koren
Journal:  Ther Drug Monit       Date:  2008-04       Impact factor: 3.681

7.  Effect of neonatal circumcision on pain responses during vaccination in boys.

Authors:  A Taddio; M Goldbach; M Ipp; B Stevens; G Koren
Journal:  Lancet       Date:  1995-02-04       Impact factor: 79.321

8.  The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta.

Authors:  E Pollex; A Lubetsky; G Koren
Journal:  Placenta       Date:  2008-06-16       Impact factor: 3.481

9.  RETIRED: Pre-conceptional vitamin/folic acid supplementation 2007: the use of folic acid in combination with a multivitamin supplement for the prevention of neural tube defects and other congenital anomalies.

Authors:  R Douglas Wilson
Journal:  J Obstet Gynaecol Can       Date:  2007-12
  9 in total

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