Literature DB >> 23616318

Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy.

Ravi Prakah Sasankoti Mohan1, Khushboo Rastogi, Rajarshi Bhushan, Sankalp Verma.   

Abstract

Drug-induced gingival enlargement is the term now used to describe medication-related gingival hypertrophy or hyperplasia, a condition commonly induced by three main classes of drugs: anticonvulsants, antihypertensive calcium channel blockers and the immunosuppressant cyclosporine. The pathogenesis of drug-induced gingival enlargement is uncertain and there appears to be no unifying hypothesis that links together the three commonly implicated drugs. Phenytoin-induced gingival overgrowth is a well known and frequently reported gingival lesion, which was first detected in 1939. This case report consists of phenytoin usage, duration and poor oral hygiene.

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Year:  2013        PMID: 23616318      PMCID: PMC3645126          DOI: 10.1136/bcr-2013-008679

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  2 in total

Review 1.  Diphenylhydantoin gingival hyperplasia. A clinicopathological review. 1. Incidence, clinical features and histopathology.

Authors:  A P Angelopoulos
Journal:  Dent J       Date:  1975-02

2.  Prevalence and risk of gingival enlargement in patients treated with anticonvulsant drugs.

Authors:  L Brunet; J Miranda; P Roset; L Berini; M Farré; C Mendieta
Journal:  Eur J Clin Invest       Date:  2001-09       Impact factor: 4.686

  2 in total
  3 in total

Review 1.  Oral manifestation in inflammatory bowel disease: a review.

Authors:  Kamran B Lankarani; Gholam Reza Sivandzadeh; Shima Hassanpour
Journal:  World J Gastroenterol       Date:  2013-12-14       Impact factor: 5.742

2.  Photodynamic therapy for the successful management of cyclosporine-related gum hypertrophy: A novel therapeutic option.

Authors:  Cinzia Casu; Martina Salvatorina Murgia; Germano Orrù; Alessandra Scano
Journal:  J Public Health Res       Date:  2022-10-06

Review 3.  Drug-induced gingival overgrowth: A critical insight into case reports from over two decades.

Authors:  Pramod Samudrala; Vijay Kumar Chava; Tanguturi Sri Chandana; Rachakonda Suresh
Journal:  J Indian Soc Periodontol       Date:  2016 Sep-Oct
  3 in total

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