Literature DB >> 23615792

Further research needed to support a policy of antiretroviral therapy as an HIV prevention initiative.

Alison J Rodger1, Tina Bruun, Pietro Vernazza, Simon Collins, Vicente Estrada, Jan Van Lunzen, Giulio M Corbelli, Andrew N Phillips, Jens D Lundgren.   

Abstract

The results from the HPTN 052 trial have increased the focus on use of antiretroviral therapy (ART) for prevention of HIV transmission; however, condom use also effectively prevents HIV transmission. Studies in heterosexual serodiscordant couples with viral suppression have so far only reported follow-up data for 330 couple-years when condoms were not being used. Data are even more limited for anal sex in men who have sex with men. Additional data on the effectiveness of ART as prevention when practicing condom-less sex is urgently needed.

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Year:  2013        PMID: 23615792     DOI: 10.3851/IMP2609

Source DB:  PubMed          Journal:  Antivir Ther        ISSN: 1359-6535


  3 in total

Review 1.  HIV treatment as prevention in men who have sex with men: examining the evidence.

Authors:  Patrick O'Byrne; Paul MacPherson
Journal:  CMAJ       Date:  2015-12-22       Impact factor: 8.262

2.  HIV Transmission Risk Persists During the First 6 Months of Antiretroviral Therapy.

Authors:  Andrew Mujugira; Connie Celum; Robert W Coombs; James D Campbell; Patrick Ndase; Allan Ronald; Edwin Were; Elizabeth A Bukusi; Nelly Mugo; James Kiarie; Jared M Baeten
Journal:  J Acquir Immune Defic Syndr       Date:  2016-08-15       Impact factor: 3.731

3.  Attitudes of people in the UK with HIV who Are Antiretroviral (ART) Naïve to starting ART at high CD4 counts for potential health benefit or to prevent HIV transmission.

Authors:  Alison J Rodger; Andrew Phillips; Andrew Speakman; Richard Gilson; Martin Fisher; Ed Wilkins; Jane Anderson; Margaret Johnson; Rebecca O'Connell; Simon Collins; Jonathan Elford; Lorraine Sherr; Fiona C Lampe
Journal:  PLoS One       Date:  2014-05-28       Impact factor: 3.240

  3 in total

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