| Literature DB >> 23615723 |
Swapan S Jain1, Craig M Anderson, Francesca DiRienzo, Isabelle R Taylor, Kyan Jain, Sumedha Guha, Nushrat Hoque.
Abstract
AH197, a trinuclear Ru(III)/Pt(II) metal complex, is strikingly more effective than the hallmark anticancer drug cisplatin and the Ru(III) clinical candidate NAMI-A in its binding to RNA and inhibition of primer DNA synthesis. Heteromultinuclear complexes could potentially serve as far better chemotherapeutics than mononuclear complexes.Entities:
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Year: 2013 PMID： 23615723 DOI： 10.1039/c3cc40699g
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222