| Literature DB >> 23611614 |
Kathryn J Rowland1, Pamela M Choi, Brad W Warner.
Abstract
Necrotizing enterocolitis (NEC) is a devastating intestinal disease resulting in major neonatal morbidity and mortality. The pathology is poorly understood, and the means of preventing and treating NEC are limited. Several endogenous growth factors have been identified as having important roles in intestinal growth as well as aiding intestinal repair from injury or inflammation. In this review, we will discuss several growth factors as mediators of intestinal regeneration and repair as well as potential therapeutic agents for NEC.Entities:
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Year: 2013 PMID: 23611614 PMCID: PMC3635039 DOI: 10.1053/j.sempedsurg.2013.01.007
Source DB: PubMed Journal: Semin Pediatr Surg ISSN: 1055-8586 Impact factor: 2.754