Literature DB >> 23611607

Optimisation of hepatocellular carcinoma surveillance in patients with viral hepatitis: a quality improvement study.

N A Kennedy1, A Rodgers, R Altus, R McCormick, R Wundke, A J Wigg.   

Abstract

BACKGROUND: Surveillance for hepatocellular carcinoma (HCC) with 6-monthly ultrasound is a standard of care for higher-risk patients with viral hepatitis. Adherence to screening guidelines is an important quality indicator in hepatology, but multiple studies have demonstrated poor HCC surveillance practices in real-world settings. AIMS: The aim of this project was to audit and then optimise HCC surveillance of viral hepatitis patients, who fulfilled criteria for screening, associated with a large tertiary hospital.
METHODS: Clinical practice improvement principles were utilised. A baseline audit of 22 consecutive viral hepatitis patients was performed. Major barriers preventing adequate surveillance were identified and three interventions to improve adherence to guidelines were introduced. These included: improved doctor education, system redesign and improved patient education. The effects of interventions were measured by serial random audits of patients. A final audit occurred over 3 years after the initial baseline audit.
RESULTS: At baseline, 46% and 0% of patients had appropriate surveillance performed during the prior 6 months (one surveillance cycle) and 2 years (four surveillance cycles) respectively. Three years after initiation of these strategies, a final audit revealed 92% (vs 46% at baseline) and 64% (vs 0% at baseline) of patients had appropriate HCC surveillance performed during the preceding 6 months and 2 years intervals respectively (P < 0.001 in each case).
CONCLUSIONS: Simple and low-cost interventions can considerably improve the clinical effectiveness of HCC screening programmes in real world settings. Clinical practice improvement principles appear to be a valid methodology for achieving this positive change.
© 2013 The Authors; Internal Medicine Journal © 2013 Royal Australasian College of Physicians.

Entities:  

Keywords:  alphafetoprotein; cirrhosis; hepatitis C; hepatocellular carcinoma; ultrasound

Mesh:

Year:  2013        PMID: 23611607     DOI: 10.1111/imj.12166

Source DB:  PubMed          Journal:  Intern Med J        ISSN: 1444-0903            Impact factor:   2.048


  9 in total

Review 1.  Quality Improvement in Gastroenterology: A Systematic Review of Practical Interventions for Clinicians.

Authors:  Courtney Reynolds; Eric Esrailian; Daniel Hommes
Journal:  Dig Dis Sci       Date:  2018-07-16       Impact factor: 3.199

Review 2.  Patient-, Provider-, and System-Level Barriers to Surveillance for Hepatocellular Carcinoma in High-Risk Patients in the USA: a Scoping Review.

Authors:  Eliza W Beal; Mackenzie Owen; Molly McNamara; Ann Scheck McAlearney; Allan Tsung
Journal:  J Gastrointest Cancer       Date:  2022-07-26

Review 3.  Quality of Cancer Care in Patients with Cirrhosis and Hepatocellular Carcinoma.

Authors:  Renumathy Dhanasekaran; Jayant A Talwalkar
Journal:  Curr Gastroenterol Rep       Date:  2015-09

4.  Improved Survival of Hepatocellular Carcinoma Patients Diagnosed with a Dedicated Screening Programme-a Propensity Score Adjusted Analysis.

Authors:  Mohamed A Chinnaratha; Kirsty Campbell; Ryan Mathias; Rosemary J McCormick; Richard J Woodman; Alan J Wigg
Journal:  J Gastrointest Cancer       Date:  2019-12

Review 5.  Surveillance for early diagnosis of hepatocellular carcinoma: how best to do it?

Authors:  Edoardo G Giannini; Alessandro Cucchetti; Virginia Erroi; Francesca Garuti; Federica Odaldi; Franco Trevisani
Journal:  World J Gastroenterol       Date:  2013-12-21       Impact factor: 5.742

6.  Use of Hepatocellular Carcinoma Surveillance in Patients With Cirrhosis: A Systematic Review and Meta-Analysis.

Authors:  Erin Wolf; Nicole E Rich; Jorge A Marrero; Neehar D Parikh; Amit G Singal
Journal:  Hepatology       Date:  2020-11-20       Impact factor: 17.425

7.  Understanding how and why audits work in improving the quality of hospital care: A systematic realist review.

Authors:  Lisanne Hut-Mossel; Kees Ahaus; Gera Welker; Rijk Gans
Journal:  PLoS One       Date:  2021-03-31       Impact factor: 3.240

8.  Patient-Reported Barriers Are Associated With Receipt of Hepatocellular Carcinoma Surveillance in a Multicenter Cohort of Patients With Cirrhosis.

Authors:  Amit G Singal; Jasmin A Tiro; Caitlin C Murphy; James-Michael Blackwell; Jennifer R Kramer; Aisha Khan; Yan Liu; Song Zhang; Jessica L Phillips; Ruben Hernaez
Journal:  Clin Gastroenterol Hepatol       Date:  2020-07-03       Impact factor: 11.382

Review 9.  Screening for Hepatocellular Carcinoma in Patients with Hepatitis B.

Authors:  Yashasavi Sachar; Mayur Brahmania; Renumathy Dhanasekaran; Stephen E Congly
Journal:  Viruses       Date:  2021-07-08       Impact factor: 5.048

  9 in total

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