Literature DB >> 23609839

The influence of large clinical trials in orthopedic trauma: do they change practice?

Hassan Khan1, Nasir Hussain, Mohit Bhandari.   

Abstract

OBJECTIVES: To evaluate the influence of top fracture trials on the practice of orthopedic surgeons.
DESIGN: This is a cross-sectional study. PARTICIPANTS: We electronically administered the survey to all members of the Canadian Orthopedic Association. We received responses for 222 surveys, of which, 178 surveys were completed. INTERVENTION: We distributed a survey that evaluated the influence of 7 important fracture studies (6 randomized controlled trials and 1 prospective cohort study) on practice, patient care and the overall advancement of knowledge in the field of orthopedics. This study was approved by our local ethics review board. MAIN OUTCOME MEASURE: The primary outcome measure was the perceived general influence and impact of important fracture studies on the perceptions and practice of orthopedic surgeons.
RESULTS: The Clavicular Fixation Trial (2007) and Tibial Fracture Trial (SPRINT, 2008) were perceived by surgeons to have the greatest influence on advancing overall knowledge in the field, improving personal practice, and the most influence on improving patient care. On the other hand, the Bone Stimulation in Fractures Trial (2011) and the recombinant human bone morphogenetic protein-2-BESST Trial (2002) had the lowest mean influence ranks. The probability of changing practice was significantly higher (Odds Ratio, 2.89; 95% confidence interval, 2.16-3.88; P < 0.00001) when studies had positive outcomes in comparison with negative outcomes.
CONCLUSIONS: Despite the complexity and costs associated with clinical trials in orthopedic trauma, the results from this survey suggest that these studies result in a demonstrable perceived influence and impact on the practice of orthopedic surgeons.

Entities:  

Mesh:

Year:  2013        PMID: 23609839     DOI: 10.1097/BOT.0b013e31829642f9

Source DB:  PubMed          Journal:  J Orthop Trauma        ISSN: 0890-5339            Impact factor:   2.512


  9 in total

1.  Has the Level of Evidence of Podium Presentations at the Musculoskeletal Tumor Society Annual Meeting Changed Over Time?

Authors:  Daniel M Lerman; Matthew G Cable; Patrick Thornley; Nathan Evaniew; Gerard P Slobogean; Mohit Bhandari; John H Healey; R Lor Randall; Michelle Ghert
Journal:  Clin Orthop Relat Res       Date:  2017-03       Impact factor: 4.176

2.  CORR Insights®: What Is the Best Evidence for Management of Displaced Midshaft Clavicle Fractures? A Systematic Review and Network Meta-analysis of 22 Randomized Controlled Trials.

Authors:  Maximiliano Ranalletta
Journal:  Clin Orthop Relat Res       Date:  2020-02       Impact factor: 4.755

3.  CHAracteristics of research studies that iNfluence practice: a GEneral survey of Canadian orthopaedic Surgeons (CHANGES): a pilot survey.

Authors:  Patrick Thornley; Nathan Evaniew; Kim Madden; Mohit Bhandari; Michelle Ghert; Darren de Sa
Journal:  Springerplus       Date:  2015-02-05

4.  An international survey to identify the intrinsic and extrinsic factors of research studies most likely to change orthopaedic practice.

Authors:  P Thornley; D de Sa; N Evaniew; F Farrokhyar; M Bhandari; M Ghert
Journal:  Bone Joint Res       Date:  2016-04       Impact factor: 5.853

5.  Appropriate care for orthopedic patients: effect of implementation of the Clinical Practice Guideline for Diagnosis and Treatment of Subacromial Pain Syndrome in the Netherlands.

Authors:  Egbert J D Veen; Martin Stevens; Cornelis T Koorevaar; Ron L Diercks
Journal:  Acta Orthop       Date:  2019-04-01       Impact factor: 3.717

6.  Operative treatment of displaced midshaft clavicle fractures: has randomised control trial evidence changed practice patterns?

Authors:  Prism Schneider; Richard Bransford; Edward Harvey; Julie Agel
Journal:  BMJ Open       Date:  2019-09-04       Impact factor: 2.692

Review 7.  Quality assessment of controlled clinical trials published in Orthopaedics and Traumatology journals in Spanish: An observational study through handsearching and evidence mapping.

Authors:  Ingrid Arevalo-Rodriguez; Edgar Muñoz; Diana Buitrago-Garcia; Solange Nuñez-González; Nadia Montero-Oleas; Vanessa Garzón; Hector Pardo-Hernandez; Xavier Bonfill
Journal:  SAGE Open Med       Date:  2018-10-03

8.  APPLICABILITY OF RANDOMIZED TRIALS IN HAND SURGERY: SURVEY STUDY.

Authors:  Vinícius Ynoe DE Moraes; Priscila Frantz Ruff; Carlos Henrique Fernandes; João Baptista Gomes Dos Santos; João Carlos Belloti; Flávio Faloppa
Journal:  Acta Ortop Bras       Date:  2018 May-Jun       Impact factor: 0.513

9.  Utilization of Orthobiologics by Sports Medicine Physicians: A Survey-based Study.

Authors:  Peter C Noback; Claire A Donnelley; Nicholas C Yeatts; Robert L Parisien; James E Fleischli; Christopher S Ahmad; Claude T Moorman; David P Trofa; Bryan M Saltzman
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2021-01-06
  9 in total

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