Literature DB >> 23606565

Antibody-functionalized magnetic polymersomes: in vivo targeting and imaging of bone metastases using high resolution MRI.

Line Pourtau1, Hugo Oliveira, Julie Thevenot, Yali Wan, Alain R Brisson, Olivier Sandre, Sylvain Miraux, Eric Thiaudiere, Sébastien Lecommandoux.   

Abstract

Multifunctional polymersomes loaded with maghemite nanoparticles and grafted with an antibody, directed against human endothelial receptor 2, are developed as novel MRI contrast agents for bone metastasis imaging. Upon administration in mice bearing bone tumor grown from human breast cancer cells, MR images show targeting and enhanced retention of antibody-labeled polymersomes at the tumor site.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  bone tumor; magnetic resonance imaging; polymersome; targeting

Mesh：

Substances：

Year:  2013        PMID： 23606565     DOI： 10.1002/adhm.201300061

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  15 in total

1.  A simple method for the synthesis of porous polymeric vesicles and their application as MR contrast agents.

Authors:  Lesan Yan; Elizabeth Higbee; Andrew Tsourkas; Zhiliang Cheng
Journal:  J Mater Chem B       Date:  2015-11-11       Impact factor: 6.331

Review 2.  Polymersome-based drug-delivery strategies for cancer therapeutics.

Authors:  Tayebeh Anajafi; Sanku Mallik
Journal:  Ther Deliv       Date:  2015

Review 3.  Nanoparticles for imaging and treatment of metastatic breast cancer.

Authors:  Qingxin Mu; Hui Wang; Miqin Zhang
Journal:  Expert Opin Drug Deliv       Date:  2016-07-19       Impact factor: 6.648

4.  Towards self-assembled hybrid artificial cells: novel bottom-up approaches to functional synthetic membranes.

Authors:  Roberto J Brea; Michael D Hardy; Neal K Devaraj
Journal:  Chemistry       Date:  2015-07-06       Impact factor: 5.236

5.  Biomaterials for Orthopaedic Diagnostics and Theranostics.

Authors:  Marian A Ackun-Farmmer; Clyde T Overby; Brittany E Haws; Regine Choe; Danielle S W Benoit
Journal:  Curr Opin Biomed Eng       Date:  2021-06-08

Review 6.  Development of individualized anti-metastasis strategies by engineering nanomedicines.

Authors:  Qianjun He; Shengrong Guo; Zhiyong Qian; Xiaoyuan Chen
Journal:  Chem Soc Rev       Date:  2015-06-09       Impact factor: 54.564

Review 7.  Engineering Polymersomes for Diagnostics and Therapy.

Authors:  Jiayu Leong; Jye Yng Teo; Vinay K Aakalu; Yi Yan Yang; Hyunjoon Kong
Journal:  Adv Healthc Mater       Date:  2018-01-15       Impact factor: 9.933

8.  Delivery of size-controlled long-circulating polymersomes in solid tumours, visualized by quantum dots and optical imaging in vivo.

Authors:  Rumiana Bakalova; Desislava Lazarova; Biliana Nikolova; Severina Atanasova; Genoveva Zlateva; Zhivko Zhelev; Ichio Aoki
Journal:  Biotechnol Biotechnol Equip       Date:  2014-11-26       Impact factor: 1.632

Review 9.  Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases.

Authors:  J A Smith; T Leonardi; B Huang; N Iraci; B Vega; S Pluchino
Journal:  Biogerontology       Date:  2014-06-28       Impact factor: 4.277

Review 10.  Smart Cargo Delivery System based on Mesoporous Nanoparticles for Bone Disease Diagnosis and Treatment.

Authors:  Panpan Pan; Qin Yue; Juan Li; Meiqi Gao; Xuanyu Yang; Yuan Ren; Xiaowei Cheng; Penglei Cui; Yonghui Deng
Journal:  Adv Sci (Weinh)       Date:  2021-03-16       Impact factor: 16.806
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