Literature DB >> 23606461

Photoswitchable particles for on-demand degradation and triggered release.

Tae-Hong Park1, Thomas W Eyster, Joshua M Lumley, Sangyeul Hwang, Kyung Jin Lee, Asish Misra, Sahar Rahmani, Joerg Lahann.   

Abstract

On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biopolymers; drug delivery; electrospinning; nanoparticles; photoswitching

Mesh：

Substances：

Year:  2013        PMID： 23606461      PMCID： PMC5550892          DOI： 10.1002/smll.201201921

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  30 in total

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