| Literature DB >> 23606028 |
Rong Zhang1, Di Wang, Zhuying Xia, Chao Chen, Peng Cheng, Hui Xie, Xianghang Luo.
Abstract
Adipocytes differentiate from mesenchymal stem cells (MSCs) in a process known as adipogenesis. The programme of adipogenesis is regulated by the sequential activation of transcription factors and several signaling pathways. There is growing evidence indicating that a class of small non-coding single-stranded RNAs known as "microRNAs (miRNAs)" also are involved in this process. In this review, we summarize the biology and functional mechanisms of miRNAs in adipocyte differentiation. In addition, we further discuss the miRNAs profiling, the miRNAs function and miRNAs target prediction in the adipogenesis.Mesh：
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Year: 2013 PMID： 23606028 DOI： 10.1007/s11684-013-0252-8
Source DB: PubMed Journal: Front Med ISSN： 2095-0217 Impact factor: 4.592