Literature DB >> 23604988

Microanalysis of stomach cancer glycosaminoglycans.

Amanda Weyers1, Bo Yang, Jong-Hwan Park, Yong-Seok Kim, Sun-Moon Kim, Sang-Eok Lee, Fuming Zhang, Kyung Bok Lee, Robert J Linhardt.   

Abstract

Glycosaminoglycans (GAGS) are anionic, linear, polysaccharides involved in cell signaling. The GAG content, composition and structure of human tissue have been suggested to play a role in cancer and might provide useful diagnostic or prognostic markers. The current study examines 17 stomach tissue biopsy samples taken from normal individuals and from patients with gastric cancers. An ultrasensitive liquid chromatography (LC) - mass spectrometry assay was applied to individual biopsy samples as small 250 μg providing GAG content and disaccharide composition. The results of these analyses show a significant increase in non-sulfated chondroitin/dermatan sulfate concentration in all cancer samples when compared to normal tissues. In addition in advanced gastric cancer, a significant decrease is observed in hyaluronan.

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Year:  2013        PMID： 23604988      PMCID： PMC3769488          DOI： 10.1007/s10719-013-9476-8

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  26 in total

1.  Expression of hyaluronan receptors CD44 and RHAMM in stomach cancers: relevance with tumor progression.

Authors:  H Li; L Guo; J W Li; N Liu; R Qi; J Liu
Journal:  Int J Oncol       Date:  2000-11       Impact factor: 5.650

2.  Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product.

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3.  Heparinase III from Flavobacterium heparinum: cloning and recombinant expression in Escherichia coli.

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Journal:  Biochem Biophys Res Commun       Date:  1996-08-23       Impact factor: 3.575

4.  Ultra-performance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis.

Authors:  Bo Yang; Amanda Weyers; Jong Youn Baik; Eric Sterner; Susan Sharfstein; Shaker A Mousa; Fuming Zhang; Jonathan S Dordick; Robert J Linhardt
Journal:  Anal Biochem       Date:  2011-04-15       Impact factor: 3.365

5.  Altered content composition and structure of glycosaminoglycans and proteoglycans in gastric carcinoma.

Authors:  Achilleas D Theocharis; Demitrios H Vynios; Nikoletta Papageorgakopoulou; Spyros S Skandalis; Dimitrios A Theocharis
Journal:  Int J Biochem Cell Biol       Date:  2003-03       Impact factor: 5.085

6.  Gastric cancer.

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Journal:  Lancet       Date:  2009-07-20       Impact factor: 79.321

7.  Microscale separation of heparosan, heparan sulfate, and heparin.

Authors:  Xue Zhao; Bo Yang; Kathryn Linkens; Payel Datta; Akihiro Onishi; Fuming Zhang; Robert J Linhardt
Journal:  Anal Biochem       Date:  2012-12-21       Impact factor: 3.365

8.  Lymphatic and/or blood vessel invasion in gastric cancer: relationship with clinicopathological parameters, biological factors and prognostic significance.

Authors:  José M del Casar; María D Corte; Ana Alvarez; Isabel García; Miguel Bongera; Luis O González; José L García-Muñiz; María T Allende; Aurora Astudillo; Francisco J Vizoso
Journal:  J Cancer Res Clin Oncol       Date:  2007-07-13       Impact factor: 4.553

Review 9.  The role and regulation of tumour-associated hyaluronan.

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Journal:  Ciba Found Symp       Date:  1989

10.  Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate.

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  9 in total

1.  Glycosaminoglycans and glycolipids as potential biomarkers in lung cancer.

Authors:  Guoyun Li; Lingyun Li; Eun Ji Joo; Ji Woong Son; Young Jin Kim; Jae Ku Kang; Kyung Bok Lee; Fuming Zhang; Robert J Linhardt
Journal:  Glycoconj J       Date:  2017-08-18       Impact factor: 2.916

2.  Biomolecular analysis of matrix proteoglycans as biomarkers in non small cell lung cancer.

Authors:  Maristela P Rangel; Vanessa K de Sá; Tabatha Prieto; João Roberto M Martins; Eloísa R Olivieri; Dirce Carraro; Teresa Takagaki; Vera Luiza Capelozzi
Journal:  Glycoconj J       Date:  2018-03-03       Impact factor: 2.916

Review 3.  Biomarkers of Helicobacter pylori-associated gastric cancer.

Authors:  Cara L Cooke; Javier Torres; Jay V Solnick
Journal:  Gut Microbes       Date:  2013-07-12

4.  Glycosaminoglycans from chicken muscular stomach or gizzard.

Authors:  Yin Chen; Megan Reddy; Yanlei Yu; Fuming Zhang; Robert J Linhardt
Journal:  Glycoconj J       Date:  2016-10-17       Impact factor: 2.916

5.  Workflow for combined proteomics and glycomics profiling from histological tissues.

Authors:  Lilla Turiák; Chun Shao; Le Meng; Kshitij Khatri; Nancy Leymarie; Qi Wang; Harry Pantazopoulos; Deborah R Leon; Joseph Zaia
Journal:  Anal Chem       Date:  2014-09-24       Impact factor: 6.986

6.  Changes in composition and sulfation patterns of glycoaminoglycans in renal cell carcinoma.

Authors:  Ebru Ucakturk; Orkun Akman; Xiaojun Sun; Dilek Ertoy Baydar; Anil Dolgun; Fuming Zhang; Robert J Linhardt
Journal:  Glycoconj J       Date:  2015-12-14       Impact factor: 2.916

7.  Primary ovarian carcinomas and abdominal metastasis contain 4,6-disulfated chondroitin sulfate rich regions, which provide adhesive properties to tumour cells.

Authors:  Myrtille J E Vallen; Samuel Schmidt; Arie Oosterhof; Johan Bulten; Leon F A G Massuger; Toin H van Kuppevelt
Journal:  PLoS One       Date:  2014-11-05       Impact factor: 3.240

8.  Chondroitin sulfate synthase 1 enhances proliferation of glioblastoma by modulating PDGFRA stability.

Authors:  Wen-Chieh Liao; Chih-Kai Liao; To-Jung Tseng; Ying-Jui Ho; Ying-Ru Chen; Kuan-Hung Lin; Te-Jen Lai; Chyn-Tair Lan; Kuo-Chen Wei; Chiung-Hui Liu
Journal:  Oncogenesis       Date:  2020-02-04       Impact factor: 7.485

Review 9.  The dual role of the glycosaminoglycan chondroitin-6-sulfate in the development, progression and metastasis of cancer.

Authors:  Adam Pudełko; Grzegorz Wisowski; Krystyna Olczyk; Ewa Maria Koźma
Journal:  FEBS J       Date:  2019-02-05       Impact factor: 5.542
  9 in total

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