OBJECTIVE: To determine our single centre experience of long term renal function and mortality rates of our cohort of spina bifida patients born since 1970. MATERIALS AND METHODS: We collected a prospective database and included all patients born with spina bifida between 1970 and 2011 managed by our centre. Data we collected included the glomerular filtration rates, results of renal tract imaging, management strategies and mortalities. RESULTS: Of 160 patients identified, 120 were included for analysis with a mean age of 20 years. In our cohort 48% (58/120) had normal renal function and only 1.6% (2/120) had severe renal impairment or end stage renal failure. There was a mortality rate of 4.4% and there were no deaths from renal failure. CONCLUSION: Spina bifida patients have been reported to have high mortality rates and high morbidity secondary to renal failure. Historical data does not appear to reflect current advancements and we would therefore be more optimistic when counselling families about long term survival into adulthood.
OBJECTIVE: To determine our single centre experience of long term renal function and mortality rates of our cohort of spina bifidapatients born since 1970. MATERIALS AND METHODS: We collected a prospective database and included all patients born with spina bifida between 1970 and 2011 managed by our centre. Data we collected included the glomerular filtration rates, results of renal tract imaging, management strategies and mortalities. RESULTS: Of 160 patients identified, 120 were included for analysis with a mean age of 20 years. In our cohort 48% (58/120) had normal renal function and only 1.6% (2/120) had severe renal impairment or end stage renal failure. There was a mortality rate of 4.4% and there were no deaths from renal failure. CONCLUSION:Spina bifidapatients have been reported to have high mortality rates and high morbidity secondary to renal failure. Historical data does not appear to reflect current advancements and we would therefore be more optimistic when counselling families about long term survival into adulthood.
Authors: Michael H Hsieh; Hadley M Wood; Brad E Dicianno; Nienke P Dosa; Veronica Gomez-Lobo; Tej K Mattoo; Rosalia Misseri; Jenna M Norton; Kathleen J Sawin; Peter Scal; James E Wright; Robert A Star; Tamara Bavendam Journal: Urology Date: 2017-02-02 Impact factor: 2.649
Authors: David I Chu; Tiebin Liu; Priya Patel; Jonathan C Routh; Lijing Ouyang; Michelle A Baum; Earl Y Cheng; Elizabeth B Yerkes; Tamara Isakova Journal: J Urol Date: 2020-03-06 Impact factor: 7.450
Authors: James T Rague; Jeremy D Lai; Peggy Murphy; Andrea Fawcett; Ryan Walton; Ilina Rosoklija; Diana K Bowen; Elizabeth B Yerkes; Earl Y Cheng; Kavita S Hodgkins; Jonathan C Routh; Tamara Isakova; David I Chu Journal: J Urol Date: 2022-01-20 Impact factor: 7.600
Authors: David I Chu; Lauren C Balmert; Liqi Chen; Cameron Arkin; Theresa Meyer; Ilina Rosoklija; Diana K Bowen; Kavita S Hodgkins; Robin M Bowman; Earl Y Cheng; Elizabeth B Yerkes; Tamara Isakova Journal: J Urol Date: 2020-11-18 Impact factor: 7.450
Authors: Diana K Bowen; Lauren C Balmert; Theresa Meyer; Ilina Rosoklija; Kavita S Hodgkins; Cybele Ghossein; Earl Y Cheng; Elizabeth B Yerkes; Tamara Isakova; David I Chu Journal: Urology Date: 2020-11-24 Impact factor: 2.649