Literature DB >> 23601170

Alcohol-induced osteopenia among in-custody and homicide deaths from the Harris County Institute of Forensic Sciences.

Heather Backo1, Jennifer Love.   

Abstract

Four cases of in-custody or unlawful death are presented as examples of increased bone fragility with an associated increase in fracture rates due to ethanol-induced osteopenia. In addition, one of the individuals suffered fractures several weeks premortem, allowing some healing to take place. Using radiographs and physical examination, the ribs from these individuals are compared with those retained from three individuals with no history of alcoholism to illustrate diagnostic characteristics that will be notable using standard autopsy and anthropological procedures. Trabecular bone mass is notably decreased in the alcoholic group leading to a greater chance of fracture occurring during conflict, including arrest and in-custody situations. The average number of perimortem fractures among the alcoholic individuals is 15, while the control group is six. In the case of the individual with healing, the degree of bone repair on the ribs was less than is expected considering the interval between injury and death.
© 2013 American Academy of Forensic Sciences.

Entities:  

Keywords:  blunt force trauma; ethanol abuse; ethanol-induced bone disease; forensic anthropology; forensic science; fracture rates; healing; osteopenia; rib fractures

Mesh:

Year:  2013        PMID: 23601170     DOI: 10.1111/1556-4029.12150

Source DB:  PubMed          Journal:  J Forensic Sci        ISSN: 0022-1198            Impact factor:   1.832


  2 in total

1.  All-trans retinoic acid can antagonize osteoblastogenesis induced by different BMPs irrespective of their dimerization types and dose-efficiencies.

Authors:  Yi Liu; Xiaoqing Ma; Jing Guo; Zhen Lin; Miao Zhou; Wenjuan Bi; Jinsong Liu; Jingxiao Wang; Haiping Lu; Gang Wu
Journal:  Drug Des Devel Ther       Date:  2018-10-10       Impact factor: 4.162

2.  The Antagonist of Retinoic Acid Receptor α, ER-50891 Antagonizes the Inhibitive Effect of All-Trans Retinoic Acid and Rescues Bone Morphogenetic Protein 2-Induced Osteoblastogenic Differentiation.

Authors:  Siqian Wang; Wenjuan Bi; Yi Liu; Jiayi Cheng; Wei Sun; Gang Wu; Xin Xu
Journal:  Drug Des Devel Ther       Date:  2020-01-22       Impact factor: 4.162

  2 in total

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