OBJECTIVE: To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa. METHODS: Sera of 796 children aged 1-15 years were tested for presence of antibodies against phase II of C. burnetii by ELISA. RESULTS: IgG and/or IgM phase II antibodies against C. burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4 years. CONCLUSIONS: Exposure to C. burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.
OBJECTIVE: To estimate the prevalence of antibodies against Coxiella burnetii (Q fever) among children in eight villages in The Gambia, West Africa. METHODS: Sera of 796 children aged 1-15 years were tested for presence of antibodies against phase II of C. burnetii by ELISA. RESULTS: IgG and/or IgM phase II antibodies against C. burnetii were detectable in 8.3% (66/796) of all serum samples analysed with significant differences in seroprevalence between villages. Highest prevalence was found in the age group 1-4 years. CONCLUSIONS: Exposure to C. burnetii is considerable in the early years of life in The Gambia, and further studies are warranted to estimate the role of Q fever in acute febrile illness in The Gambia and elsewhere in Africa.
Authors: Ashley L Greiner; Saithip Bhengsri; Matthieu Million; Sophie Edouard; Somsak Thamthitiwat; Kevin Clarke; Gilbert J Kersh; Christopher J Gregory; Didier Raoult; Philippe Parola Journal: Am J Trop Med Hyg Date: 2018-01 Impact factor: 2.345
Authors: J Njeru; K Henning; M W Pletz; R Heller; C Forstner; S Kariuki; E M Fèvre; H Neubauer Journal: BMC Infect Dis Date: 2016-06-03 Impact factor: 3.090
Authors: Nicola A Wardrop; Lian F Thomas; Elizabeth A J Cook; William A de Glanville; Peter M Atkinson; Claire N Wamae; Eric M Fèvre Journal: PLoS Negl Trop Dis Date: 2016-10-07
Authors: Sruti Pisharody; Matthew P Rubach; Manuela Carugati; William L Nicholson; Jamie L Perniciaro; Holly M Biggs; Michael J Maze; Julian T Hertz; Jo E B Halliday; Kathryn J Allan; Blandina T Mmbaga; Wilbrod Saganda; Bingileki F Lwezaula; Rudovick R Kazwala; Sarah Cleaveland; Venance P Maro; John A Crump Journal: Am J Trop Med Hyg Date: 2021-12-20 Impact factor: 2.345
Authors: Sky Vanderburg; Matthew P Rubach; Jo E B Halliday; Sarah Cleaveland; Elizabeth A Reddy; John A Crump Journal: PLoS Negl Trop Dis Date: 2014-04-10