BACKGROUND: Risk scores show difficulties to attain the same performance in different populations. OBJECTIVE: To create a simple and accurate risk assessment model for patients submitted to surgery due to coronary and/or valvular disease at Instituto do Coração da Universidade de São Paulo (InCor-HCFMUSP). METHODS: Between 2007 and 2009, 3,000 patients were submitted to surgical procedure due to coronary artery and/or valvular disease at InCor-HCFMUSP. From this record, data of 2/3 of the patients were used for model development (bootstrap technique), and 1/3 for internal validation of the model. The performance of the model (InsCor) was compared to the 2000 Bernstein-Parsonnet (2000BP) and EuroSCORE (ES) complexes. RESULTS: Only 10 variables were selected: age > 70 years, female sex; coronary revascularization + valve, myocardial infarction < 90 days; reoperation; surgical treatment of aortic valve; surgical treatment of tricuspid valve; creatinine < 2mg/dL; ejection fraction < 30%, and events. The Hosmer Lemeshow test for the InsCor was 0.184, indicating excellent calibration. The area under the ROC curve was 0.79 for the InsCor, 0.81 for the ES and 0.82 for 2000BP, confirming that the models are good and have similar discrimination. CONCLUSIONS: The InsCor and ES performed better than 2000BP at all stages of validation, but the new model, in addition to showing identification with the local risk factors, is simpler and more objective for mortality prediction in patients undergoing surgery due to coronary and/or valvular disease at InCor-HCFMUSP.
BACKGROUND: Risk scores show difficulties to attain the same performance in different populations. OBJECTIVE: To create a simple and accurate risk assessment model for patients submitted to surgery due to coronary and/or valvular disease at Instituto do Coração da Universidade de São Paulo (InCor-HCFMUSP). METHODS: Between 2007 and 2009, 3,000 patients were submitted to surgical procedure due to coronary artery and/or valvular disease at InCor-HCFMUSP. From this record, data of 2/3 of the patients were used for model development (bootstrap technique), and 1/3 for internal validation of the model. The performance of the model (InsCor) was compared to the 2000 Bernstein-Parsonnet (2000BP) and EuroSCORE (ES) complexes. RESULTS: Only 10 variables were selected: age > 70 years, female sex; coronary revascularization + valve, myocardial infarction < 90 days; reoperation; surgical treatment of aortic valve; surgical treatment of tricuspid valve; creatinine < 2mg/dL; ejection fraction < 30%, and events. The Hosmer Lemeshow test for the InsCor was 0.184, indicating excellent calibration. The area under the ROC curve was 0.79 for the InsCor, 0.81 for the ES and 0.82 for 2000BP, confirming that the models are good and have similar discrimination. CONCLUSIONS: The InsCor and ES performed better than 2000BP at all stages of validation, but the new model, in addition to showing identification with the local risk factors, is simpler and more objective for mortality prediction in patients undergoing surgery due to coronary and/or valvular disease at InCor-HCFMUSP.
Authors: Lisandro Gonçalves Azeredo; Elinthon Tavares Veronese; José Augusto Duncan Santiago; Carlos Manuel de Almeida Brandão; Pablo Maria Alberto Pomerantzeff; Fabio Biscegli Jatene Journal: Rev Bras Cir Cardiovasc Date: 2014 Jul-Sep
Authors: Ricardo Casalino; Flávio Tarasoutchi; Guilherme Spina; Marcelo Katz; Antonio Bacelar; Roney Sampaio; Otavio T Ranzani; Pablo M Pomerantzeff; Max Grinberg Journal: PLoS One Date: 2015-02-25 Impact factor: 3.240
Authors: Camila P S Arthur; Omar A V Mejia; Diogo Osternack; Marcelo Arruda Nakazone; Maxim Goncharov; Luiz A F Lisboa; Luís A O Dallan; Pablo M A Pomerantzeff; Fabio B Jatene Journal: Arq Bras Cardiol Date: 2017-09-04 Impact factor: 2.000
Authors: Luiz Augusto Ferreira Lisboa; Omar Asdrubal Vilca Mejia; Luiz Felipe Pinho Moreira; Luís Alberto Oliveira Dallan; Pablo Maria Alberto Pomerantzeff; Luís Roberto Palma Dallan; Maria Raquel B Massoti; Fabio B Jatene Journal: Rev Bras Cir Cardiovasc Date: 2014 Jan-Mar