Literature DB >> 23597546

Tuberous sclerosis complex associated with heterotopic ossification in a young girl.

Teck-King Tan1, Fong-Lin Chen1, Ji-Nan Sheu2, Shan-Ming Chen2, Hsin-Hui Huang3, Jeng-Dau Tsai4.   

Abstract

Tuberous sclerosis complex (TSC) is a multisystem disorder resulting in hamartomatous lesions. Despite diverse manifestations, skeletal muscular comorbidity is rarely reported in TSC. We report a 2-year-old girl with TSC who suffered from multiple subcutaneous masses over the paraspinal and bilateral scapular areas, which caused disabling pain on any passive movement. Three-dimensional computed tomography scanning revealed multiple calcifications that were consequently diagnosed as fibrodysplasia ossificans progressiva. Such imaging features should be evaluated cautiously to avoid unnecessary surgical intervention and biopsy that may worsen the condition.
Copyright © 2012. Published by Elsevier B.V.

Entities:  

Keywords:  fibrodysplasia ossificans progressive; heterotopic ossificans; tuberous sclerosis complex

Mesh:

Year:  2013        PMID: 23597546     DOI: 10.1016/j.pedneo.2012.12.002

Source DB:  PubMed          Journal:  Pediatr Neonatol        ISSN: 1875-9572            Impact factor:   2.083


  1 in total

1.  Association between the growth rate of subependymal giant cell astrocytoma and age in patients with tuberous sclerosis complex.

Authors:  Jeng-Dau Tsai; Chang-Ching Wei; Teng-Fu Tsao; Yu-Ping Hsiao; Henry J Tsai; Sheng-Hui Yang; Min-Ling Tsai; Ji-Nan Sheu
Journal:  Childs Nerv Syst       Date:  2015-11-09       Impact factor: 1.475

  1 in total

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