OBJECTIVES: The current study investigates heart rate variability (HRV) responses to a psychosocial stressor in chronic obstructive pulmonary disease (COPD) patients, and the potential role of anxiety as a confounding factor in this relationship. Additionally, this study also investigates the influence of anxiety on sleep and depressive symptoms among COPD patients. METHODS: The study utilized a 2 (disease status)×2 (anxiety group) factorial design examining HRV associated with anxiety symptoms and COPD during a standardized acute social stress task. Participants (mean age 59.1±11.2 years; 50% female) completed pulmonary function testing, HRV monitoring, and self-report questionnaires assessing psychological factors. 30 COPD patients were age- and gender-matched with 30 healthy controls. RESULTS: HRV response to a psychosocial stressor among participants with higher anxiety (both COPD and healthy) reflected autonomic dysregulation in both time and frequency domains that was not evident among non-anxious participants. COPD participants with higher anxiety reported greater symptoms of depression and poorer sleep quality than did COPD participants with low anxiety. CONCLUSIONS: Anxiety is associated with dysregulated HRV response to a psychosocial stressor, but the negative influence of anxiety and COPD on autonomic function did not appear to be additive. Comorbid anxiety in patients with COPD is associated with increased behavioral and psychological symptoms of distress.
OBJECTIVES: The current study investigates heart rate variability (HRV) responses to a psychosocial stressor in chronic obstructive pulmonary disease (COPD) patients, and the potential role of anxiety as a confounding factor in this relationship. Additionally, this study also investigates the influence of anxiety on sleep and depressive symptoms among COPDpatients. METHODS: The study utilized a 2 (disease status)×2 (anxiety group) factorial design examining HRV associated with anxiety symptoms and COPD during a standardized acute social stress task. Participants (mean age 59.1±11.2 years; 50% female) completed pulmonary function testing, HRV monitoring, and self-report questionnaires assessing psychological factors. 30 COPDpatients were age- and gender-matched with 30 healthy controls. RESULTS: HRV response to a psychosocial stressor among participants with higher anxiety (both COPD and healthy) reflected autonomic dysregulation in both time and frequency domains that was not evident among non-anxious participants. COPDparticipants with higher anxiety reported greater symptoms of depression and poorer sleep quality than did COPDparticipants with low anxiety. CONCLUSIONS:Anxiety is associated with dysregulated HRV response to a psychosocial stressor, but the negative influence of anxiety and COPD on autonomic function did not appear to be additive. Comorbid anxiety in patients with COPD is associated with increased behavioral and psychological symptoms of distress.
Authors: Zafar A Usmani; Kristin V Carson; Karen Heslop; Adrian J Esterman; Anthony De Soyza; Brian J Smith Journal: Cochrane Database Syst Rev Date: 2017-03-21
Authors: Luenda E Charles; Michael E Andrew; Khachatur Sarkisian; Li Shengqiao; Anna Mnatsakanova; John M Violanti; Mark Wilson; Ja K Gu; Diane B Miller; Cecil M Burchfiel Journal: Am J Hum Biol Date: 2013-10-18 Impact factor: 1.937
Authors: Adriano L Roque; Vitor E Valenti; Thais Massetti; Talita Dias da Silva; Carlos Bandeira de Mello Monteiro; Fernando R Oliveira; Álvaro Dantas de Almeida Junior; Sheylla Nadjane Batista Lacerda; Gustavo Carreiro Pinasco; Viviane Gabriela Nascimento; Luiz Gonzaga Granja Filho; Luiz Carlos de Abreu; David M Garner; Celso Ferreira Journal: Int Arch Med Date: 2014-10-03