Literature DB >> 23596124

From a multipotent stilbene to soluble epoxide hydrolase inhibitors with antiproliferative properties.

Estella Buscató1, Dominik Büttner, Astrid Brüggerhoff, Franca-Maria Klingler, Julia Weber, Bastian Scholz, Aleksandra Zivković, Rolf Marschalek, Holger Stark, Dieter Steinhilber, Helge B Bode, Ewgenij Proschak.   

Abstract

Inspired by nature: Natural product isopropylstilbene was identified as an inhibitor of soluble epoxide hydrolase exhibiting antiproliferative properties. Following the natural product inspired design approach, a library of (E)-styryl-1H-benzo[d]imidazoles was synthesized and evaluated with recombinant enzyme and on several cancer cell lines.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID： 23596124     DOI： 10.1002/cmdc.201300057

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


  9 in total

1.  Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo.

Authors:  Seiya Kitamura; Christophe Morisseau; Bora Inceoglu; Shizuo G Kamita; Gina R De Nicola; Maximilienne Nyegue; Bruce D Hammock
Journal:  PLoS One       Date:  2015-02-06       Impact factor: 3.240

2.  Genome comparisons provide insights into the role of secondary metabolites in the pathogenic phase of the Photorhabdus life cycle.

Authors:  Nicholas J Tobias; Bagdevi Mishra; Deepak K Gupta; Rahul Sharma; Marco Thines; Timothy P Stinear; Helge B Bode
Journal:  BMC Genomics       Date:  2016-08-03       Impact factor: 3.969

3.  From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity.

Authors:  Geraldine Mulley; Michael L Beeton; Paul Wilkinson; Isabella Vlisidou; Nina Ockendon-Powell; Alexia Hapeshi; Nick J Tobias; Friederike I Nollmann; Helge B Bode; Jean van den Elsen; Richard H ffrench-Constant; Nicholas R Waterfield
Journal:  PLoS One       Date:  2015-12-17       Impact factor: 3.240

4.  Screening of the Antimicrobial Activity against Drug Resistant Bacteria of Photorhabdus and Xenorhabdus Associated with Entomopathogenic Nematodes from Mae Wong National Park, Thailand.

Authors:  Paramaporn Muangpat; Temsiri Yooyangket; Chamaiporn Fukruksa; Manawat Suwannaroj; Thatcha Yimthin; Sutthirat Sitthisak; Narisara Chantratita; Apichat Vitta; Nicholas J Tobias; Helge B Bode; Aunchalee Thanwisai
Journal:  Front Microbiol       Date:  2017-06-28       Impact factor: 5.640

5.  Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales.

Authors:  Seiya Kitamura; Christophe Morisseau; Todd R Harris; Bora Inceoglu; Bruce D Hammock
Journal:  PLoS One       Date:  2017-05-04       Impact factor: 3.240

6.  Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening.

Authors:  Veronika Temml; Ulrike Garscha; Erik Romp; Gregor Schubert; Jana Gerstmeier; Zsofia Kutil; Barbara Matuszczak; Birgit Waltenberger; Hermann Stuppner; Oliver Werz; Daniela Schuster
Journal:  Sci Rep       Date:  2017-02-20       Impact factor: 4.379

Review 7.  Small Molecule Soluble Epoxide Hydrolase Inhibitors in Multitarget and Combination Therapies for Inflammation and Cancer.

Authors:  Amarjyoti Das Mahapatra; Rinku Choubey; Bhaskar Datta
Journal:  Molecules       Date:  2020-11-24       Impact factor: 4.411

8.  Genome analysis of secondary metabolite‑biosynthetic gene clusters of Photorhabdus akhurstii subsp. akhurstii and its antibacterial activity against antibiotic-resistant bacteria.

Authors:  Paramaporn Muangpat; Wipanee Meesil; Jatuporn Ngoenkam; Yothin Teethaisong; Rapee Thummeepak; Sutthirat Sitthisak; Sarunporn Tandhavanant; Narisara Chantratita; Helge B Bode; Apichat Vitta; Aunchalee Thanwisai
Journal:  PLoS One       Date:  2022-09-21       Impact factor: 3.752

9.  A study on Xenorhabdus and Photorhabdus isolates from Northeastern Thailand: Identification, antibacterial activity, and association with entomopathogenic nematode hosts.

Authors:  Thatcha Yimthin; Chamaiporn Fukruksa; Paramaporn Muangpat; Abdulhakam Dumidae; Wandee Wattanachaiyingcharoen; Apichat Vitta; Aunchalee Thanwisai
Journal:  PLoS One       Date:  2021-08-12       Impact factor: 3.240
  9 in total

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