Literature DB >> 23595792

Progress in Alzheimer's disease research in the last year.

Daniela Galimberti1, Elio Scarpini.   

Abstract

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, with a prevalence of 5 % after 65 years of age, increasing to about 30 % in people aged 85 years or older. It is characterized by progressive cognitive impairment, including impaired judgment, decision-making and orientation, and in some cases accompanied by psycho behavioral disturbances or language impairment. Herein, we summarize and discuss the main articles describing novel findings in AD published over the last year, including clinical, therapeutic, and research issues.

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Year:  2013        PMID: 23595792     DOI: 10.1007/s00415-013-6921-3

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  25 in total

1.  Stereotypic behaviors in degenerative dementias.

Authors:  S Prioni; V Fetoni; F Barocco; V Redaelli; C Falcone; P Soliveri; F Tagliavini; A Scaglioni; P Caffarra; L Concari; S Gardini; F Girotti
Journal:  J Neurol       Date:  2012-05-31       Impact factor: 4.849

2.  Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease.

Authors:  Holly D Soares; William Z Potter; Eve Pickering; Max Kuhn; Frederick W Immermann; David M Shera; Mats Ferm; Robert A Dean; Adam J Simon; Frank Swenson; Judith A Siuciak; June Kaplow; Madhav Thambisetty; Panayiotis Zagouras; Walter J Koroshetz; Hong I Wan; John Q Trojanowski; Leslie M Shaw
Journal:  Arch Neurol       Date:  2012-10

3.  Cerebrospinal fluid levels of β-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia.

Authors:  Peder Buchhave; Lennart Minthon; Henrik Zetterberg; Asa K Wallin; Kaj Blennow; Oskar Hansson
Journal:  Arch Gen Psychiatry       Date:  2012-01

4.  Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.

Authors:  Sudad Saman; WonHee Kim; Mario Raya; Yvonne Visnick; Suhad Miro; Sarmad Saman; Bruce Jackson; Ann C McKee; Victor E Alvarez; Norman C Y Lee; Garth F Hall
Journal:  J Biol Chem       Date:  2011-11-04       Impact factor: 5.157

5.  Executive dysfunction in frontotemporal dementia is related to abnormalities in frontal white matter tracts.

Authors:  M C Tartaglia; Y Zhang; C Racine; V Laluz; J Neuhaus; L Chao; J Kramer; H Rosen; B Miller; M Weiner
Journal:  J Neurol       Date:  2011-10-29       Impact factor: 4.849

6.  Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia.

Authors:  Renaud La Joie; Audrey Perrotin; Louisa Barré; Caroline Hommet; Florence Mézenge; Méziane Ibazizene; Vincent Camus; Ahmed Abbas; Brigitte Landeau; Denis Guilloteau; Vincent de La Sayette; Francis Eustache; Béatrice Desgranges; Gaël Chételat
Journal:  J Neurosci       Date:  2012-11-14       Impact factor: 6.167

7.  miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model.

Authors:  Soon-Tae Lee; Kon Chu; Keun-Hwa Jung; Jin Hee Kim; Ji-Young Huh; Hyejin Yoon; Dong-Kyu Park; Ji-Yeon Lim; Jeong-Min Kim; Daejong Jeon; Hoon Ryu; Sang Kun Lee; Manho Kim; Jae-Kyu Roh
Journal:  Ann Neurol       Date:  2012-08       Impact factor: 10.422

8.  Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study.

Authors:  Eric M Reiman; Yakeel T Quiroz; Adam S Fleisher; Kewei Chen; Carlos Velez-Pardo; Marlene Jimenez-Del-Rio; Anne M Fagan; Aarti R Shah; Sergio Alvarez; Andrés Arbelaez; Margarita Giraldo; Natalia Acosta-Baena; Reisa A Sperling; Brad Dickerson; Chantal E Stern; Victoria Tirado; Claudia Munoz; Rebecca A Reiman; Matthew J Huentelman; Gene E Alexander; Jessica B S Langbaum; Kenneth S Kosik; Pierre N Tariot; Francisco Lopera
Journal:  Lancet Neurol       Date:  2012-11-06       Impact factor: 44.182

9.  Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study.

Authors:  Daniel H J Davis; Graciela Muniz Terrera; Hannah Keage; Terhi Rahkonen; Minna Oinas; Fiona E Matthews; Colm Cunningham; Tuomo Polvikoski; Raimo Sulkava; Alasdair M J MacLullich; Carol Brayne
Journal:  Brain       Date:  2012-08-09       Impact factor: 13.501

10.  Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.

Authors:  Mason A Israel; Shauna H Yuan; Cedric Bardy; Sol M Reyna; Yangling Mu; Cheryl Herrera; Michael P Hefferan; Sebastiaan Van Gorp; Kristopher L Nazor; Francesca S Boscolo; Christian T Carson; Louise C Laurent; Martin Marsala; Fred H Gage; Anne M Remes; Edward H Koo; Lawrence S B Goldstein
Journal:  Nature       Date:  2012-01-25       Impact factor: 49.962

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  4 in total

Review 1.  Neurological update: dementia.

Authors:  A J Larner
Journal:  J Neurol       Date:  2014-02-06       Impact factor: 4.849

2.  Cognitive and neuropsychiatric impairments in Alzheimer's disease: current treatment strategies.

Authors:  Anna Borisovskaya; Marcella Pascualy; Soo Borson
Journal:  Curr Psychiatry Rep       Date:  2014-09       Impact factor: 5.285

Review 3.  Cardiovascular effects of drugs used to treat Alzheimer's disease.

Authors:  Laurence Guy Howes
Journal:  Drug Saf       Date:  2014-06       Impact factor: 5.606

4.  A clinico-epidemiological study of cognitive function status of community-dwelling elderly.

Authors:  Indarjeet Singh Gambhir; Vishal Khurana; Dhiraj Kishore; Ashutosh K Sinha; S C Mohapatra
Journal:  Indian J Psychiatry       Date:  2014-10       Impact factor: 1.759

  4 in total

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