Literature DB >> 23595174

An ulcerated nodule on the nose.

Catriona M Maybury1, Emma Craythorne, Blanca Martin.   

Abstract

A 75-year-old retired nurse, originally from Barbados, presented to her general practitioner (GP) with a scaling ulcerated nodule on the left side of her nose. She was taking medication for type 2 diabetes, hypertension and glaucoma, but was otherwise well with no systemic symptoms. Her GP diagnosed a patch of eczema; however, a trial of topical steroids was not effective and she was referred to dermatology. A skin biopsy confirmed the clinical suspicion that this patient had a nodular basal cell carcinoma (BCC). BCCs account for 75% of all skin cancers; they very rarely metastasise, but can spread to invade local structures. Our patient has type VI skin. Skin cancer is rare in patients with skin type VI; however, in this group, morbidity and mortality are disproportionately high in relation to cancer incidence.

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Mesh:

Year:  2013        PMID: 23595174      PMCID: PMC3644923          DOI: 10.1136/bcr-2012-008296

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

Review 1.  Molecular aetiology and pathogenesis of basal cell carcinoma.

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Journal:  Br J Dermatol       Date:  2005-06       Impact factor: 9.302

Review 2.  Guidelines for the management of basal cell carcinoma.

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Journal:  Br J Dermatol       Date:  2008-07       Impact factor: 9.302

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Authors:  T B Fitzpatrick
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Review 4.  Basal cell carcinoma: cell of origin, cancer stem cell hypothesis and stem cell markers.

Authors:  K Sellheyer
Journal:  Br J Dermatol       Date:  2011-03-16       Impact factor: 9.302

Review 5.  Skin cancer in skin of color.

Authors:  Hugh M Gloster; Kenneth Neal
Journal:  J Am Acad Dermatol       Date:  2006-11       Impact factor: 11.527

6.  Risk factors for single and multiple basal cell carcinomas.

Authors:  Ville Kiiski; Esther de Vries; Sophie C Flohil; Monique J Bijl; Albert Hofman; Bruno H C Stricker; Tamar Nijsten
Journal:  Arch Dermatol       Date:  2010-08

7.  Sunlight exposure, pigmentation factors, and risk of nonmelanocytic skin cancer. II. Squamous cell carcinoma.

Authors:  R P Gallagher; G B Hill; C D Bajdik; A J Coldman; S Fincham; D I McLean; W J Threlfall
Journal:  Arch Dermatol       Date:  1995-02

8.  Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.

Authors:  Daniel D Von Hoff; Patricia M LoRusso; Charles M Rudin; Josina C Reddy; Robert L Yauch; Raoul Tibes; Glen J Weiss; Mitesh J Borad; Christine L Hann; Julie R Brahmer; Howard M Mackey; Bertram L Lum; Walter C Darbonne; James C Marsters; Frederic J de Sauvage; Jennifer A Low
Journal:  N Engl J Med       Date:  2009-09-02       Impact factor: 91.245

  8 in total

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