Literature DB >> 23592698

Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound.

Stefan T Yohe1, Jonathan A Kopechek, Tyrone M Porter, Yolonda L Colson, Mark W Grinstaff.   

Abstract

Application of high-intensity focused ultrasound to drug-loaded superhydrophobic meshes affords triggered drug release by displacing an entrapped air layer. The air layer within the superhydrophobic meshes is characterized using direct visualization and B-mode imaging. Drug-loaded superhydrophobic meshes are cytotoxic in an in vitro assay after ultrasound treatment.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  HIFU; biomaterials; drug delivery; electrospinning; meshes; superhydrophobic; triggered; ultrasound

Mesh：

Substances：

Year:  2013        PMID： 23592698      PMCID： PMC3923359          DOI： 10.1002/adhm.201200381

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


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