Literature DB >> 23587636

First characterization of a digital SiPM based time-of-flight PET detector with 1 mm spatial resolution.

Stefan Seifert1, Gerben van der Lei, Herman T van Dam, Dennis R Schaart.   

Abstract

Monolithic scintillator detectors can offer a combination of spatial resolution, energy resolution, timing performance, depth-of-interaction information, and detection efficiency that make this type of detector a promising candidate for application in clinical, time-of-flight (TOF) positron emission tomography (PET). In such detectors the scintillation light is distributed over a relatively large number of photosensor pixels and the light intensity per pixel can be relatively low. Therefore, monolithic scintillator detectors are expected to benefit from the low readout noise offered by a novel photosensor called the digital silicon photomultiplier (dSiPM). Here, we present a first experimental characterization of a TOF PET detector comprising a 24 × 24 × 10 mm(3) LSO:Ce,0.2%Ca scintillator read out by a dSiPM array (DPC-6400-44-22) developed by Philips Digital Photon Counting. A spatial resolution of ~1 mm full-width-at-half-maximum (FWHM) averaged over the entire crystal was obtained (varying from just below 1 mm FWHM in the detector center to ~1.2 mm FWHM close to the edges). Furthermore, the bias in the position estimation at the crystal edges that is typically found in monolithic scintillators is well below 1 mm even in the corners of the crystal.

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Year:  2013        PMID: 23587636     DOI: 10.1088/0031-9155/58/9/3061

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  20 in total

Review 1.  Innovations in Instrumentation for Positron Emission Tomography.

Authors:  Eric Berg; Simon R Cherry
Journal:  Semin Nucl Med       Date:  2018-03-12       Impact factor: 4.446

2.  Side readout of long scintillation crystal elements with digital SiPM for TOF-DOI PET.

Authors:  Jung Yeol Yeom; Ruud Vinke; Craig S Levin
Journal:  Med Phys       Date:  2014-12       Impact factor: 4.071

3.  Modularized compact positron emission tomography detector for rapid system development.

Authors:  Daoming Xi; Xiang Liu; Chen Zeng; Wei Liu; Yanzhao Li; Yuexuan Hua; Xiongze Mei; Heejong Kim; Peng Xiao; Chien-Min Kao; Qingguo Xie
Journal:  J Med Imaging (Bellingham)       Date:  2016-12-20

Review 4.  Update on novel trends in PET/CT technology and its clinical applications.

Authors:  Stephan Walrand; Michel Hesse; François Jamar
Journal:  Br J Radiol       Date:  2016-11-25       Impact factor: 3.039

5.  Compton PET: A Simulation Study for a PET Module with Novel Geometry and Machine Learning for Position Decoding.

Authors:  Peng Peng; Martin S Judenhofer; Adam Q Jones; Simon R Cherry
Journal:  Biomed Phys Eng Express       Date:  2018-11-30

6.  Total Body PET: Why, How, What for?

Authors:  Suleman Surti; Austin R Pantel; Joel S Karp
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2020-04-03

7.  Using convolutional neural networks to estimate time-of-flight from PET detector waveforms.

Authors:  Eric Berg; Simon R Cherry
Journal:  Phys Med Biol       Date:  2018-01-11       Impact factor: 3.609

8.  Evaluation of event position reconstruction in monolithic crystals that are optically coupled.

Authors:  M Morrocchi; W C J Hunter; A Del Guerra; T K Lewellen; P E Kinahan; L R MacDonald; M G Bisogni; R S Miyaoka
Journal:  Phys Med Biol       Date:  2016-11-03       Impact factor: 3.609

9.  Development of a prototype PET scanner with depth-of-interaction measurement using solid-state photomultiplier arrays and parallel readout electronics.

Authors:  Yiping Shao; Xishan Sun; Kejian A Lan; Chad Bircher; Kai Lou; Zhi Deng
Journal:  Phys Med Biol       Date:  2014-02-20       Impact factor: 3.609

Review 10.  Advances in time-of-flight PET.

Authors:  Suleman Surti; Joel S Karp
Journal:  Phys Med       Date:  2016-01-06       Impact factor: 2.685

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