Literature DB >> 23586536

A further assessment of the Hall-Rodriguez theory of latent inhibition.

Hiu Tin Leung1, A S Killcross, R Frederick Westbrook.   

Abstract

The Hall-Rodriguez (G. Hall & G. Rodriguez, 2010, Associative and nonassociative processes in latent inhibition: An elaboration of the Pearce-Hall model, in R. E. Lubow & I. Weiner, Eds., Latent inhibition: Data, theories, and applications to schizophrenia, pp. 114-136, Cambridge, England: Cambridge University Press) theory of latent inhibition predicts that it will be deepened when a preexposed target stimulus is given additional preexposures in compound with (a) a novel stimulus or (b) another preexposed stimulus, and (c) that deepening will be greater when the compound contains a novel rather than another preexposed stimulus. A series of experiments studied these predictions using a fear conditioning procedure with rats. In each experiment, rats were preexposed to 3 stimuli, 1 (A) taken from 1 modality (visual or auditory) and the remaining 2 (X and Y) taken from another modality (auditory or visual). Then A was compounded with X, and Y was compounded with a novel stimulus (B) taken from the same modality as A. A previous series of experiments (H. T. Leung, A. S. Killcross, & R. F. Westbrook, 2011, Additional exposures to a compound of two preexposed stimuli deepen latent inhibition, Journal of Experimental Psychology: Animal Behavior Processes, Vol. 37, pp. 394-406) compared A with Y, finding that A was more latently inhibited than Y, the opposite of what was predicted. The present experiments confirmed that A was more latently inhibited than Y, showed that this was due to A entering the compound more latently inhibited than Y, and finally, that a comparison of X and Y confirmed the 3 predictions made by the theory.

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Year:  2013        PMID: 23586536     DOI: 10.1037/a0031724

Source DB:  PubMed          Journal:  J Exp Psychol Anim Behav Process        ISSN: 0097-7403


  1 in total

1.  Error correction in latent inhibition and its disruption by opioid receptor blockade with naloxone.

Authors:  Hiu T Leung; A S Killcross; R Frederick Westbrook
Journal:  Neuropsychopharmacology       Date:  2013-06-10       Impact factor: 7.853

  1 in total

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