Literature DB >> 23585236

Incorporation of 6-thioguanine nucleotides into DNA during maintenance therapy of childhood acute lymphoblastic leukemia-the influence of thiopurine methyltransferase genotypes.

Maria S Ebbesen1, Jacob Nersting, Jack H Jacobsen, Thomas L Frandsen, Kim Vettenranta, Jonas Abramsson, Finn Wesenberg, Kjeld Schmiegelow.   

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Year:  2013        PMID： 23585236     DOI： 10.1002/jcph.81

Source DB:  PubMed          Journal:  J Clin Pharmacol        ISSN： 0091-2700            Impact factor:   3.126


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  17 in total

1.  NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.

Authors:  Takaya Moriyama; Rina Nishii; Virginia Perez-Andreu; Wenjian Yang; Federico Antillon Klussmann; Xujie Zhao; Ting-Nien Lin; Keito Hoshitsuki; Jacob Nersting; Kentaro Kihira; Ute Hofmann; Yoshihiro Komada; Motohiro Kato; Robert McCorkle; Lie Li; Katsuyoshi Koh; Cesar Rolando Najera; Shirley Kow-Yin Kham; Tomoya Isobe; Zhiwei Chen; Edwynn Kean-Hui Chiew; Deepa Bhojwani; Cynthia Jeffries; Yan Lu; Matthias Schwab; Hiroto Inaba; Ching-Hon Pui; Mary V Relling; Atsushi Manabe; Hiroki Hori; Kjeld Schmiegelow; Allen E J Yeoh; William E Evans; Jun J Yang
Journal:  Nat Genet       Date:  2016-02-15       Impact factor: 38.330

2.  Oral administration of non-absorbable delayed release 6-mercaptopurine is locally active in the gut, exerts a systemic immune effect and alleviates Crohn's disease with low rate of side effects: results of double blind Phase II clinical trial.

Authors:  E Israeli; E Goldin; S Fishman; F Konikoff; A Lavy; Y Chowers; E Melzer; A Lahat; M Mahamid; H Shirin; E Nussinson; O Segol; A Ben Ya'acov; Y Shabbat; Y Ilan
Journal:  Clin Exp Immunol       Date:  2015-08       Impact factor: 4.330

3.  Mechanisms of NT5C2-Mediated Thiopurine Resistance in Acute Lymphoblastic Leukemia.

Authors:  Takaya Moriyama; Shuguang Liu; Jing Li; Julia Meyer; Xujie Zhao; Wentao Yang; Youming Shao; Richard Heath; Aleš Hnízda; William L Carroll; Jun J Yang
Journal:  Mol Cancer Ther       Date:  2019-07-29       Impact factor: 6.261

4.  Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity.

Authors:  Mette Levinsen; Susanne Rosthøj; Ulrikka Nygaard; Jesper Heldrup; Arja Harila-Saari; Olafur G Jonsson; Anne Grete Bechensteen; Jonas Abrahamsson; Birgitte Lausen; Thomas L Frandsen; Richard M Weinshilboum; Kjeld Schmiegelow
Journal:  Cancer Chemother Pharmacol       Date:  2014-10-28       Impact factor: 3.333

5.  Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy.

Authors:  Rina Nishii; Takaya Moriyama; Laura J Janke; Wenjian Yang; Chase C Suiter; Ting-Nien Lin; Lie Li; Kentaro Kihira; Hidemi Toyoda; Ute Hofmann; Matthias Schwab; Masatoshi Takagi; Tomohiro Morio; Atsushi Manabe; Shirley Kham; Nan Jiang; Karen R Rabin; Motohiro Kato; Katsuyoshi Koh; Allen Eng-Juh Yeoh; Hiroki Hori; Jun J Yang
Journal:  Blood       Date:  2018-03-23       Impact factor: 22.113

Review 6.  Association of NUDT15 c.415C>T allele and thiopurine-induced leukocytopenia in Asians: a systematic review and meta-analysis.

Authors:  A L Zhang; J Yang; H Wang; J L Lu; S Tang; X J Zhang
Journal:  Ir J Med Sci       Date:  2017-05-03       Impact factor: 1.568

7.  Dynamics of leucocyte DNA thioguanine nucleotide levels during maintenance therapy of childhood acute lymphoblastic leukemia.

Authors:  Rikke Hebo Larsen; Lisa Lyngsie Hjalgrim; Matilda Degn; Jacob Nersting; Bodil Als-Nielsen; Kathrine Grell; Kjeld Schmiegelow
Journal:  Cancer Chemother Pharmacol       Date:  2021-03-23       Impact factor: 3.333

8.  Interaction between NUDT15 and ABCC4 variants enhances intolerability of 6-mercaptopurine in Japanese patients with childhood acute lymphoblastic leukemia.

Authors:  Y Tanaka; H Nakadate; K Kondoh; K Nakamura; K Koh; A Manabe
Journal:  Pharmacogenomics J       Date:  2017-04-18       Impact factor: 3.550

9.  Thiopurine S-methyltransferase testing for averting drug toxicity in patients receiving thiopurines: a systematic review.

Authors:  Lilla M Roy; Richard M Zur; Elizabeth Uleryk; Chris Carew; Shinya Ito; Wendy J Ungar
Journal:  Pharmacogenomics       Date:  2016-03-29       Impact factor: 2.533

Review 10.  [Research advances in pharmacogenomics of mercaptopurine].

Authors:  Xiao-Xiao Chen; Shu-Hong Shen
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2017-09
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