Literature DB >> 23584791

Prenatal diagnosis of multicystic dysplastic kidney disease in the second trimester screening.

Ammar Al Naimi1, Jan-Eric Baumüller, Stephan Spahn, Franz Bahlmann.   

Abstract

OBJECTIVE: Multicystic dysplastic kidney (MCDK) is the most common antenatally diagnosed cystic renal pathology. It refers to the presence of multiple kidney cysts surrounded by dysplastic parenchymal tissue. The typical MCDK ultrasound finding shows multiple nonconnecting thin-walled cysts within an irregularly outlined kidney. We want to present our own cases as an addition to the relatively scarce literature about MCDK.
METHOD: We retrospectively review 54 cases (21 bilateral and 33 unilateral) with antenatally diagnosed MCDK between the years 1998 and 2012. We compare our data with the published literature and discuss different parameters.
RESULTS: Our findings show a male predominance of 1.8 : 1 and a left side/right side ratio of 0.73 : 1. Most of the cases were isolated findings, but 20.3% were associated with anomalies. One case was a Goldenhar syndrome. Of the bilateral MCDK cases, 14.3% had chromosomal defects. The mean gestational age at time of diagnosis was 20-21 weeks. Renal length was above the 90th normal percentile in 96.2% of the cases.
CONCLUSION: Isolated unilateral MCDK has good prognosis. Bad prognosis is linked to association with other anomalies as well as to bilateral MCDK.
© 2013 John Wiley & Sons, Ltd.

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Mesh:

Year:  2013        PMID: 23584791     DOI: 10.1002/pd.4112

Source DB:  PubMed          Journal:  Prenat Diagn        ISSN: 0197-3851            Impact factor:   3.050


  4 in total

1.  Positive predictive value and completeness of prenatally assigned International Classification of Disease-10 kidney anomaly diagnoses in the Danish National Patient Registry.

Authors:  Maria Rasmussen; Morten Smærup Olsen; Lone Sunde; Lars Pedersen; Olav Bjørn Petersen
Journal:  Clin Epidemiol       Date:  2016-01-18       Impact factor: 4.790

2.  Minimally invasive open nephrectomy on children with multicystic dysplastic kidney.

Authors:  Dongchuan Feng; Xiaoyu Zhu; Fang Sun; Tongsheng Ma; Yuan Li; Shujing Chen
Journal:  Exp Ther Med       Date:  2016-10-18       Impact factor: 2.447

3.  [Prenatal diagnosis of multicystic dysplastic kidney: about 18 cases].

Authors:  Hekmat Chaara; Hind Adadi; Imane Attar; Sofia Jayi; Fatima-Zahra Fdili Alaoui; Moulay Abdelilah Melhouf
Journal:  Pan Afr Med J       Date:  2019-07-31

4.  Outcome of Multi-Cystic Dysplastic Kidneys in Children.

Authors:  Suleiman D Mashat; Sherif M El-Desoky; Jameela Abdulaziz Kari
Journal:  Iran J Pediatr       Date:  2015-10-06       Impact factor: 0.364

  4 in total

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