Literature DB >> 23584564

NPMc+ and FLT3_ITD mutations cooperate in inducing acute leukaemia in a novel mouse model.

M Mallardo1, A Caronno, G Pruneri, P R Raviele, A Viale, P G Pelicci, E Colombo.   

Abstract

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Year:  2013        PMID： 23584564     DOI： 10.1038/leu.2013.114

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  24 in total

1.  Overexpression of FLT3-ITD driven by spi-1 results in expanded myelopoiesis with leukemic phenotype in zebrafish.

Authors:  J-W Lu; H-A Hou; M-S Hsieh; H-F Tien; L-I Lin
Journal:  Leukemia       Date:  2016-05-20       Impact factor: 11.528

2.  NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia.

Authors:  Alina Rudorf; Tony Andreas Müller; Cathrin Klingeberg; Stefanie Kreutmair; Teresa Poggio; Sivahari Prasad Gorantla; Tamina Rückert; Annette Schmitt-Graeff; Anina Gengenbacher; Peter Paschka; Claudia Baldus; Robert Zeiser; George S Vassiliou; Allan Bradley; Justus Duyster; Anna Lena Illert
Journal:  Blood       Date:  2019-06-11       Impact factor: 22.113

3.  Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.

Authors:  Yiting Lim; Lukasz Gondek; Li Li; Qiuju Wang; Hayley Ma; Haley Ma; Emily Chang; David L Huso; Sarah Foerster; Luigi Marchionni; Karen McGovern; David Neil Watkins; Craig D Peacock; Mark Levis; Bruce Douglas Smith; Akil A Merchant; Donald Small; William Matsui
Journal:  Sci Transl Med       Date:  2015-06-10       Impact factor: 17.956

4.  PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias.

Authors:  C Ronchini; A Brozzi; L Riva; L Luzi; A M Gruszka; G E M Melloni; E Scanziani; G Dharmalingam; M Mutarelli; V Belcastro; S Lavorgna; V Rossi; O Spinelli; A Biondi; A Rambaldi; F Lo-Coco; D di Bernardo; P G Pelicci
Journal:  Leukemia       Date:  2016-12-27       Impact factor: 11.528

Review 5.  Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.

Authors:  P Sportoletti; E Varasano; R Rossi; A Mupo; E Tiacci; G Vassiliou; M P Martelli; B Falini
Journal:  Leukemia       Date:  2014-09-02       Impact factor: 11.528

6.  NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.

Authors:  Rachel Rau; Daniel Magoon; Sarah Greenblatt; Li Li; Colleen Annesley; Amy S Duffield; David Huso; Emily McIntyre; John G Clohessy; Markus Reschke; Pier Paolo Pandolfi; Donald Small; Patrick Brown
Journal:  Exp Hematol       Date:  2013-10-29       Impact factor: 3.084

7.  Mutant NPM1 Maintains the Leukemic State through HOX Expression.

Authors:  Lorenzo Brunetti; Michael C Gundry; Daniele Sorcini; Anna G Guzman; Yung-Hsin Huang; Raghav Ramabadran; Ilaria Gionfriddo; Federica Mezzasoma; Francesca Milano; Behnam Nabet; Dennis L Buckley; Steven M Kornblau; Charles Y Lin; Paolo Sportoletti; Maria Paola Martelli; Brunangelo Falini; Margaret A Goodell
Journal:  Cancer Cell       Date:  2018-09-10       Impact factor: 31.743

8.  Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.

Authors:  Oliver M Dovey; Jonathan L Cooper; Annalisa Mupo; Carolyn S Grove; Claire Lynn; Nathalie Conte; Robert M Andrews; Suruchi Pacharne; Konstantinos Tzelepis; M S Vijayabaskar; Paul Green; Roland Rad; Mark Arends; Penny Wright; Kosuke Yusa; Allan Bradley; Ignacio Varela; George S Vassiliou
Journal:  Blood       Date:  2017-08-23       Impact factor: 22.113

9.  Menin inhibition decreases Bcl-2 and synergizes with venetoclax in NPM1/FLT3-mutated AML.

Authors:  Bing Z Carter; Wenjing Tao; Po Yee Mak; Lauren B Ostermann; Duncan Mak; Gerard McGeehan; Peter Ordentlich; Michael Andreeff
Journal:  Blood       Date:  2021-10-28       Impact factor: 22.113

Review 10.  Targeting Immunophenotypic Markers on Leukemic Stem Cells: How Lessons from Current Approaches and Advances in the Leukemia Stem Cell (LSC) Model Can Inform Better Strategies for Treating Acute Myeloid Leukemia (AML).

Authors:  Kelly Mitchell; Ulrich Steidl
Journal:  Cold Spring Harb Perspect Med       Date:  2020-01-02       Impact factor: 6.915
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