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Literature DB >> 23584093

Transient Mesp1 expression: a driver of cardiac cell fate determination.

Abstract

Mesp1 sits on the tip of the cardiac regulatory hierarchy, recent evidences support that it is regulated by stem cell factor Oct4, early gastrulation signal canonical Wnts and a couple of T-box factors, T and Eomes. With other transcription factors, Mesp1 programs/reprograms human cells toward cardiomyocytes.

Entities: Gene Species

Keywords: Mesp1; embryonic stem cells; progenitor cells; reprograming; transcription factor

Mesh：

Substances：

Year: 2013 PMID： 23584093 PMCID： PMC4042590 DOI： 10.4161/trns.24588

Source DB: PubMed Journal: Transcription ISSN： 2154-1272

35 in total

1. Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development.

Authors: S Haraguchi; S Kitajima; A Takagi; H Takeda; T Inoue; Y Saga
Journal: Mech Dev Date: 2001-10 Impact factor: 1.882

Review 2. Mesp1 expression is the earliest sign of cardiovascular development.

Authors: Y Saga; S Kitajima; S Miyagawa-Tomita
Journal: Trends Cardiovasc Med Date: 2000-11 Impact factor: 6.677

3. A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells.

Authors: Stephanie Protze; Shahryar Khattak; Claire Poulet; Dirk Lindemann; Elly M Tanaka; Ursula Ravens
Journal: J Mol Cell Cardiol Date: 2012-04-28 Impact factor: 5.000

4. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells.

Authors: H Niwa; J Miyazaki; A G Smith
Journal: Nat Genet Date: 2000-04 Impact factor: 38.330

Review 5. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures.

Authors: R Grosschedl; K Giese; J Pagel
Journal: Trends Genet Date: 1994-03 Impact factor: 11.639

6. Ancestry and diversity of the HMG box superfamily.

Authors: V Laudet; D Stehelin; H Clevers
Journal: Nucleic Acids Res Date: 1993-05-25 Impact factor: 16.971

7. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.

Authors: Jose Francisco Islas; Yu Liu; Kuo-Chan Weng; Matthew J Robertson; Shuxing Zhang; Allan Prejusa; John Harger; Dariya Tikhomirova; Mani Chopra; Dinakar Iyer; Mark Mercola; Robert G Oshima; James T Willerson; Vladimir N Potaman; Robert J Schwartz
Journal: Proc Natl Acad Sci U S A Date: 2012-07-23 Impact factor: 11.205

8. Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element.

Authors: Yongqing Li; Wei Yu; Austin J Cooney; Robert J Schwartz; Yu Liu
Journal: Stem Cells Date: 2013-06 Impact factor: 6.277

Transient Mesp1 expression: a driver of cardiac cell fate determination.

1. Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development.

Review 2. Mesp1 expression is the earliest sign of cardiovascular development.

3. A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells.

4. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells.

Review 5. HMG domain proteins: architectural elements in the assembly of nucleoprotein structures.

6. Ancestry and diversity of the HMG box superfamily.

7. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.

8. Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element.

9. MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube.

10. MesP1 and MesP2 are essential for the development of cardiac mesoderm.

Review 1. Cardiac Embryology and Molecular Mechanisms of Congenital Heart Disease: A Primer for Anesthesiologists.

2. Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells.

3. How Mesp1 makes a move.

Review 4. A MicroRNA Perspective on Cardiovascular Development and Diseases: An Update.

Review 5. Cardiac Progenitor Cells from Stem Cells: Learning from Genetics and Biomaterials.