Irfan Taşoğlu1, Osman Turak2, Yunus Nazli3, Fırat Ozcan2, Necmettin Colak3, Serpil Sahin4, Kemal Kavasoglu4, Bahadır Genc4, Doğan Sert4, Mehmet Karahan4, Omer Cicek4, Ata Ecevit4. 1. Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey irfantasoglu@yahoo.com. 2. Department of Cardiology, Turkiye Yuksek Ihtisas Heart, Education and Research Hospital, Ankara, Turkey. 3. Department of Cardiovascular Surgery, Fatih Unıversty Medical Faculty, Ankara, Turkey. 4. Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
Abstract
AIM: The aim of the present study was to investigate the predictive value of preoperative neutrophil-lymphocyte ratio (NLR) in postoperative saphenous vein graft patency in patients undergoing coronary artery bypass grafting (CABG) surgery. METHOD: We retrospectively analyzed 444 patients who had undergone CABG and a further control coronary angiography due to recurrence of symptoms. The patients were divided into tertile groups according to the NLR. The primary end point was 50% saphenous vein graft stenosis or more or complete occlusion. RESULT: The saphenous vein graft failure in the 3 groups based on NLR was 33%, 66.2%, and 79.1%, in the low-, middle- and high-risk groups, respectively. In multivariate regression modeling, current smoker, diabetes mellitus, target artery diameter <1.5 mm, and NLR independently predicted saphenous vein graft patency in patients after CABG. CONCLUSION: Preoperative NLR is clearly an independent predictor of saphenous vein graft patency in patients after CABG.
AIM: The aim of the present study was to investigate the predictive value of preoperative neutrophil-lymphocyte ratio (NLR) in postoperative saphenous vein graft patency in patients undergoing coronary artery bypass grafting (CABG) surgery. METHOD: We retrospectively analyzed 444 patients who had undergone CABG and a further control coronary angiography due to recurrence of symptoms. The patients were divided into tertile groups according to the NLR. The primary end point was 50% saphenous vein graft stenosis or more or complete occlusion. RESULT: The saphenous vein graft failure in the 3 groups based on NLR was 33%, 66.2%, and 79.1%, in the low-, middle- and high-risk groups, respectively. In multivariate regression modeling, current smoker, diabetes mellitus, target artery diameter <1.5 mm, and NLR independently predicted saphenous vein graft patency in patients after CABG. CONCLUSION: Preoperative NLR is clearly an independent predictor of saphenous vein graft patency in patients after CABG.
Authors: Tomasz Urbanowicz; Anna Olasińska-Wiśniewska; Michał Michalak; Michał Rodzki; Anna Witkowska; Ewa Straburzyńska-Migaj; Bartłomiej Perek; Marek Jemielity Journal: Biology (Basel) Date: 2021-12-27